SAGO STARCH AND SODIUM ALGINATE AS NATURAL CROSSLINKING FOR CAPSULE ALTERNATIVES

S. Harimurti, Amelia Nur'afni Mulyanti, Anisa Kusnindyasita, Hari Widada, Rifki Febriansah, Totok Suwanda, M. Muhtadi
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Abstract

Capsule shells are generally made from gelatin. The gelatin that is spread in the world is commonly derived from pigs. This animal is forbidden to be consumed by Muslims. This issue is due to the halal aspect. Sago starch and sodium alginate are halal materials that are capable of gelatinizing. This property made it able to be molded as a capsule. This research aims to determine the formula of sago and sodium alginate as a capsule and the evaluation. Three formulas were made with the ratio of sago and sodium alginate 100%: 0% (formula 1), 50%: 50% (formula 2), and 0%:  100% (formula 3). The capsule was manually molded using a food-grade stainless steel capsule mold. The size of the capsule, weight uniformity, swelling, and disintegration time were determined for a physical evaluation. SLD was used to determine the best formula, and the validation was done using One-sample T-test. The evaluations of the capsule shell were found ranged as follows:  the size specifications were 21-22 mm, the body diameter was  6.1-7.2 mm, the cap diameter was 13.6-13.8 mm, weight uniformity was 0.10-0.26 gram, the swelling test was 433-1583%, and the disintegration time was 10.20-14.43 minutes. The best formula based on the SLD of the experiment was formula 3, which are two parameters that met the requirements, i.e., swelling and disintegration time. The sago and sodium alginate were crosslinked, and the capsule was made. However, the performance dislike of gelatin capsules. Continued research shall be done to find the optimum formula and its characteristics for alternative material on halal capsules.
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西米淀粉和海藻酸钠作为胶囊替代品的天然交联剂
胶囊外壳一般由明胶制成。世界上流传的明胶通常来自猪。穆斯林禁止食用这种动物。这个问题是由于清真方面的原因造成的。西米淀粉和海藻酸钠是能够糊化的清真材料。这种特性使其能够被模塑成胶囊。本研究旨在确定西米和海藻酸钠作为胶囊的配方并进行评估。按照西米和海藻酸钠的比例,制作了三种配方:100%:0%(配方 1)、50%:50%(配方 2)和 0%:100%(配方 3): 100%(配方 3)。胶囊使用食品级不锈钢胶囊模具手工成型。对胶囊的尺寸、重量均匀性、膨胀度和崩解时间进行了物理评估。使用 SLD 确定最佳配方,并使用单样本 T 检验进行验证。对胶囊外壳的评价结果如下:尺寸规格为 21-22 毫米,囊体直径为 6.1-7.2 毫米,囊盖直径为 13.6-13.8 毫米,重量均匀性为 0.10-0.26 克,膨胀试验为 433-1583%,崩解时间为 10.20-14.43 分钟。根据实验的 SLD,最佳配方为配方 3,其膨胀度和崩解时间两项参数均符合要求。将西米和海藻酸钠交联,制成胶囊。然而,明胶胶囊的性能与之不符。应继续进行研究,以找到清真胶囊替代材料的最佳配方及其特性。
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审稿时长
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