The effect of T-lysine cream on the wound healing process

Asmaa Awni Haydar
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Abstract

Background and objective: Wound healing is a dynamic process that can be compromised in patients with chronic and metabolic conditions or unhealthy lifestyles. Objectives of study is to demonstrate a hyaluronate-containing supramolecular structure which enhances repalysYAL®cream effectiveness, sodium chloride with thymine (T-LysYal®); 1) notable progress in the healing of wounds. 2) the production of minuscule collagen strands 3) a shorter recovery period. Methods: Case study, the test group received standard treatment followed by lysine cream to indicate the size and depth ulcer from the 1st week to the 3rd week. Our patients were a 1-year child and 29 years old male who presented with a second degree of total body surface area (TBSA) burn and skin grafts at the burn center of Rozhawa Hospital/ Hawler/Iraq. The observations were approved by the Ethics committee college of pharmacy in compliance with the ethical standard. Initially assessed as superficial partial-thickness in-depth, the wounds were treated conservatively with dressings and repalysYAL® cream 2-3 times per day; however, represents the healing process in short-term individual therapy. Results: In case 1; The patient had been exposed to flash deep burn to the right palm (thermal injury) mainly of superficial partial thickness; any necrotic tissue present needs to be removed to take full advantage of the product’s potential. When (repalysYAL®) cream is used, there will be a physiological increase in the exudate, which will have to be managed to avoid maceration. While in case 2;The patient presented surgical wound dehiscence in the inner compartment of the left foot with leakage of purulent material and signs of necrotizing fasciitis. with using (repalysYAL®) cream, the wound reduces scar formation due to 90% and increase fibroblast by 30% when a blood vessel is formed to which blood is supplied, the cells are cultivated and divided to form new tissue and an organ. Conclusion: Signaling pathways that induce cellular and tissue responses after injury, which may be impeded during chronic wound healing, were greatly improved using lysine cream as a therapy.
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T-lysine 乳膏对伤口愈合过程的影响
背景和目的:伤口愈合是一个动态过程,患有慢性病、代谢性疾病或生活方式不健康的患者可能会受到影响。本研究的目的是证明一种含透明质酸的超分子结构可提高 RepalysYAL®cream 的功效,即氯化钠与胸腺嘧啶(T-LysYal®);1)显著促进伤口愈合。2)产生微小的胶原链 3)缩短恢复期。方法病例研究,试验组接受标准治疗,然后在第 1 周至第 3 周使用赖氨酸乳膏来指示溃疡的大小和深度。我们的患者是一名 1 岁的儿童和一名 29 岁的男性,他们在伊拉克罗扎瓦医院/霍勒烧伤中心接受了二度体表总面积 (TBSA) 烧伤和植皮治疗。观察结果经药学院伦理委员会批准,符合伦理标准。伤口最初被评估为浅表部分深度烧伤,使用敷料和 repalysYAL® 乳膏进行保守治疗,每天 2-3 次;然而,短期个别治疗代表了伤口的愈合过程。结果在病例 1 中,患者的右手掌受到闪灼深度烧伤(热损伤),主要是浅表部分厚度的烧伤;需要清除任何存在的坏死组织,以充分发挥产品的潜力。使用(repalysYAL®)乳膏时,渗出物会出现生理性增加,必须加以处理,以避免浸渍。使用(repalysYAL®)乳膏后,伤口的疤痕形成减少了 90%,成纤维细胞增加了 30%,当血管形成并有血液供应时,细胞得到培养和分裂,从而形成新的组织和器官。结论赖氨酸乳膏作为一种疗法,大大改善了损伤后诱导细胞和组织反应的信号通路,而这些信号通路在慢性伤口愈合过程中可能会受到阻碍。
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审稿时长
24 weeks
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