The Effects of Intraoperative Placement of Tetracycline, Tetracycline + Gelatin Sponge, and Placebo on Postoperative Dry Socket Incidence After Mandibular Molar Extraction: (A Comparative Prospective Study)

Mohammad Haykel, Thair A. Lateef
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Abstract

Background:  The aim of the study evaluation 0f tetracycline, tetracycline plus gelatin sponge efficacy in lowering dry socket incidence among patients experienced extraction procedure for mandibular molars compared to control group.. Material and Methods: The sample was divided into three groups each group have 30 patients (34 male and 56 female) :          Group A (patients dealt without intra-socket tetracycline) in which only applying figure of 8 suturing and dressing adhesive material for sockets.          Group B (patients managed with intra-socket tetracycline alone) in which patients managed after extraction with tetracycline solution, figure of 8 suturing and dressing adhesive material.          Group C (patients managed with intra-socket tetracycline plus gelatin sponge complex) in which patients managed after extraction with tetracycline-gelatin sponge vehicle, figure of 8 suturing and adhesive dressing material. Results: Dry socket following extraction was encountered in 4 female patients, with an incidence of 4.4%. Group A reported the highest number. Conclusions: In spite of the limits of this clinical trial, the placement of tetracycline as intra-socket medicament serve in a good choice for treating extracted socket, by reducing bacterial load that will result in lowering the possible chances of infection thus relieving pain, on the other hand the Ora-aid dressing material serve a good way accompanied with suturing in avoiding dry socket occurrence.
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下颌磨牙拔除术后术中放置四环素、四环素+明胶海绵和安慰剂对术后干槽症发生率的影响:(一项前瞻性比较研究)
研究背景 研究目的:与对照组相比,评估四环素、四环素加明胶海绵对降低下颌磨牙拔除术患者干槽症发生率的疗效。材料与方法:样本分为三组,每组 30 名患者(男性 34 名,女性 56 名): A 组(未使用牙槽窝内四环素的患者),仅对牙槽窝应用 8 字缝合和敷料粘合材料。 B 组(仅在牙槽内使用四环素的患者),患者在拔牙后使用四环素溶液、8 字缝合线和敷料粘合剂。 C组(患者在牙槽内使用四环素加明胶海绵复合剂),患者在拔牙后使用四环素-明胶海绵载体、8字缝合线和粘合敷料。结果显示有 4 名女性患者在拔牙后出现干槽症,发生率为 4.4%。A 组的发病率最高。结论尽管这项临床试验存在一定的局限性,但将四环素作为窝沟封闭药物是治疗拔牙窝沟封闭的一个不错选择,它能减少细菌负荷,从而降低感染的几率,减轻疼痛;另一方面,Ora-aid 敷料能很好地配合缝合,避免干槽症的发生。
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