Lung damages of malaria: a differential diagnosis and treatment in emergency room of a rare case

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Italian Journal of Medicine Pub Date : 2023-11-29 DOI:10.4081/itjm.2023.1603
N. Carannante, S. Scarica, Raffaele Disarno, Gerardo Langella, P. Di Micco, G. Fiorentino
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Abstract

Pulmonary involvement occurs in 3 to 10% of the cases of Plasmodium falciparum malaria and represents the most severe complication of this infection, with a lethality of about 70%. The antigens released by the parasite play an important role in the induction and worsening of lung damage. Capillary endothelial cells, which control the flux of fluids to the interstitial space, appear to be the most complicated structures. The clinical manifestations of pulmonary involvement may start suddenly at any time during the course of malaria, even after the disappearance of the circulating parasite. Hyperparasitemia predisposes to these factors. Treatment with corticosteroids is optional, and that is not often a benefit.
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疟疾引起的肺损伤:一例罕见病例的鉴别诊断和急诊治疗
在恶性疟原虫疟疾病例中,肺部受累的比例为 3%至 10%,是这种感染最严重的并发症,致死率约为 70%。寄生虫释放的抗原在诱发和加重肺损伤方面起着重要作用。毛细血管内皮细胞控制着体液向间质的流动,似乎是最复杂的结构。肺部受累的临床表现可能在疟疾病程的任何时候突然开始,甚至在循环寄生虫消失后也是如此。高寄生虫血症容易导致这些因素。皮质类固醇的治疗是可选的,但通常并无益处。
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来源期刊
Italian Journal of Medicine
Italian Journal of Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
3
审稿时长
10 weeks
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