Histopathology Of The Spleen; Platelet Count Of Wistar Rats Exposed To Eliozu Dumpsite Leachate

Abstract

- Eliozu dumpsite is one of the biggest dumpsite in Port Harcourt metropolis. Wastes are dumped untreated, and thus may pose serious environmental risks to inhabitants in the area. The present study focuses on the assessment of the histopathology of the spleen; platelet counts exposed to Eliozu dumpsite leachate using wistar rats as model. Twenty five (25) male wistar rats were divided into five groups of five animals each; the leachate was collected from the dumpsite and water from near-by borehole also collected. Group 1 which served as control group received 1ml of commercial bottle water, group 2 received 1ml of borehole water 1kilometer from the dumpsite, groups 3, 4 and 5 received different concentration of the leachate in 10%, 50% and 100% for (40) days, the animals were sacrificed after being anesthetized with chloroform vapor, the bloods and spleens were collected for Platelet counts were analyzed