Nanotechnologies for the detection and treatment of endometriosis

Maneesha Sahni, Emily S. Day
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Abstract

Endometriosis is an incurable gynecologic disease characterized by endometrial-like tissue growth outside of the uterine cavity. It affects approximately 10% of reproductive age women, who endure pelvic pain during periods and/or sexual intercourse and who suffer from reduced fertility and diminished quality of life due to the side effects of current treatments. To improve the management and prognosis of endometriosis patients, researchers have recently begun to develop nanoparticle-based diagnostics and treatments that are more effective and less invasive than existing approaches. This review discusses the current state of the field and highlights considerations for the continued development of nanotechnologies for the diagnosis and treatment of endometriosis.
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检测和治疗子宫内膜异位症的纳米技术
子宫内膜异位症是一种无法治愈的妇科疾病,其特征是子宫内膜样组织在子宫腔外生长。约有 10%的育龄妇女会受到这种疾病的影响,她们在经期和/或性交时会感到盆腔疼痛,而且由于目前治疗方法的副作用,她们的生育能力下降,生活质量降低。为了改善子宫内膜异位症患者的管理和预后,研究人员最近开始开发基于纳米粒子的诊断和治疗方法,这些方法比现有方法更有效、创伤更小。本综述讨论了该领域的现状,并强调了继续开发用于诊断和治疗子宫内膜异位症的纳米技术的注意事项。
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