Psychiatric morbidity among patients suffering from Vitiligo

Sandeep Kapur, Ekram Goyal, Ajay Kumar, Alka Puria, Richa Raj
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Abstract

Background: Vitiligo is a chronic acquired, stigmatizing disease characterized by discoloration of skin and mucous membranes. Patients suffering from this condition suffer from a lack of confidence and psychological stress. Aim: To assess depression, anxiety, and social anxiety among patients suffering from vitiligo. Material and Method: This hospital-based cross-sectional, observational, descriptive study was carried out in a tertiary care center on 100 patients suffering from vitiligo, who were consecutively enrolled after informed consent from the outpatient department (OPD) of the dermatology department. Permission was obtained from the institutional ethics committee Diagnosis of vitiligo was made by two consultants from the department of dermatology. Sociodemographic variables were recorded in the sociodemographic form. The General Health Questionnaire-12 (GHQ-12) was applied to all 100 patients. Patients who scored >3 on GHQ-12 were further subjected to the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and Social Interaction Anxiety Scale. Results were statistically analyzed on SPSS-22.0 (IBM, Armonk, USA). Results: Of all the patients, 55% (n = 55) had a GHQ score >3 (i.e., Psychiatric morbidity was present in 55% of patients.). Out of 50 patients in the age group of 18–25 years, 41 patients in the age groups of 26–35 years, and 9 patients in the age groups of 36–45 years, 22 (44%), 17 (42.1%), and 6 patients had psychiatric morbidity, respectively. Of the total number of patients, 46% had depression according to the HAM-D scale. Of all the patients, 18% had mild, 22% had moderate, and 6% had severe depression. Age-wise analysis showed that out of 50 patients in the age group of 18–25 years, 41 patients in the age group of 26–35 years, and 9 patients in the age group of 36–45 years, 22 (44%), 20 (48.7%), and 4 patients had depression, respectively. Of the patients who had depression, 39% were male and 58% were female. On HAM-A, 47% of the patients had anxiety; 33% had mild, 12% had moderate, and 2% had severe anxiety. Age-wise analysis showed that out of 50 patients in the age group of 18–25, 41 patients in the age group of 26–35 years, and 9 patients in the age group of 36–45 years, 20 (40%), 23 (56.1%), and 3 patients had anxiety, respectively. On SIAS, 36% of the patients had social anxiety. Out of 50 patients in the age group of 18–25 years, 41 patients in the age group of 26–35 years, and 9 patients in the age group of 36–45 years, 23 (46%), 9 (7.8%) and 4 patients had social anxiety, respectively. According to gender-wise distribution, 17% of male and 63% of female patients had social anxiety. Conclusion: A high prevalence of anxiety, depression, and social anxiety has been observed in this present study. Therefore, importance should be given to psychiatric evaluation of such patients and, if required, necessary interventions should be undertaken to improve their quality of life.
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白癜风患者的精神病发病率
背景:白癜风是一种以皮肤和粘膜脱色为特征的慢性后天性污名化疾病。该病患者缺乏自信,心理压力大。目的:评估白癜风患者的抑郁、焦虑和社交焦虑。材料与方法:这项基于医院的横断面、观察性、描述性研究在一家三级医疗中心进行,100 名白癜风患者在获得皮肤科门诊部(OPD)的知情同意后连续入组。这些患者在获得皮肤科门诊部(OPD)的知情同意后连续入选,并获得了机构伦理委员会的许可,由皮肤科的两名顾问进行白癜风诊断。社会人口学变量记录在社会人口学表格中。所有 100 名患者均采用了《一般健康问卷-12》(GHQ-12)。对 GHQ-12 得分超过 3 分的患者进一步进行了汉密尔顿抑郁评定量表(HAM-D)、汉密尔顿焦虑评定量表(HAM-A)和社会交往焦虑量表的测试。结果通过 SPSS-22.0 (IBM,美国阿蒙克)进行统计分析。结果在所有患者中,55%(n = 55)的 GHQ 得分大于 3(即 55% 的患者存在精神疾病)。在 18-25 岁年龄组的 50 名患者、26-35 岁年龄组的 41 名患者和 36-45 岁年龄组的 9 名患者中,分别有 22 名(44%)、17 名(42.1%)和 6 名患者患有精神疾病。根据 HAM-D 量表,46%的患者患有抑郁症。在所有患者中,18% 患有轻度抑郁症,22% 患有中度抑郁症,6% 患有重度抑郁症。年龄分析显示,在 50 名 18-25 岁、41 名 26-35 岁和 9 名 36-45 岁的患者中,分别有 22 人(44%)、20 人(48.7%)和 4 人患有抑郁症。在抑郁症患者中,39% 为男性,58% 为女性。在 HAM-A 中,47% 的患者有焦虑症;33% 有轻度焦虑症,12% 有中度焦虑症,2% 有重度焦虑症。年龄分析显示,在 50 名 18-25 岁、41 名 26-35 岁和 9 名 36-45 岁的患者中,分别有 20 人(40%)、23 人(56.1%)和 3 人患有焦虑症。在 SIAS 中,36% 的患者患有社交焦虑症。在 50 名 18-25 岁、41 名 26-35 岁和 9 名 36-45 岁的患者中,分别有 23 人(46%)、9 人(7.8%)和 4 人患有社交焦虑症。从性别分布来看,17%的男性患者和 63%的女性患者患有社交焦虑症。结论本研究观察到焦虑、抑郁和社交焦虑的高发病率。因此,应重视对这类患者进行精神评估,如有必要,应采取必要的干预措施来改善他们的生活质量。
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