[Effects of hyperbaric oxygenation, thalamonal and their combination on pulmonary edema in experimental embolism of blood vessels of the lesser circulation].

Abstract

Hyperbaric oxygenation leads to 100% survival of albino rats in development of fatal under normobaric conditions pulmonary edema induced by embolism of the vessels of the lesser circulation by olive oil. The degree of lung hydration and the amount of pleural effusion diminish significantly in this case but hyperemia of the pulmonary tissue persists. Thalamonal produces a moderate protective effect in fat embolism, which is manifested by reduced steeping of the lungs in fluid. Under the condition of hyperbaric oxygenation thalamonal fails to change the degree of edema and reduces slightly blood filling of the lungs in fat embolism. Hyperbaric oxygenation, thalamonal and their combination do not protect the lungs from edema and hyperemia in mechanical embolism of the vessels of the lesser circulation by lycopodium.