Liver Infiltration From a Huge Renal Cell Carcinoma: A Diagnostic and Management Enigma

Devendra Choudhary, Maktum Naik, Vageesh Bg, Anil Agarwal
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Abstract

Renal Cell Carcinoma (RCC) is the most lethal malignancy of urinary tract. Invasion of right lobe of liver by RCC is rare and possess a treatment challenge. Simultaneous nephrectomy with right hepatectomy has been proposed as a part of multi-modality treatment approach. We herein discuss a patient who underwent simultaneous nephrectomy with right hepatectomy along with single peritoneal metastasectomy for a huge RCC of right kidney and infiltrating the right lobe of liver. A 30- year old female was diagnosed with a right renal tumor invading into the right hepatic lobe. Post multi-disciplinary tumor board meeting she was planned for surgical intervention. Intra-operatively a single peritoneal nodule was present which came positive for malignancy on frozen section. Considering young age, good performance status and oligometastatic disease definitive procedure in the form of combined right nephrectomy and right hepatectomy was performed. She was discharged from the hospital on 6th post-operative day with an uneventful post-operative course. This type of RCC has been rarely reported and the combined nephrectomy and right hepatectomy is safe and feasible for this type of huge RCC invading right hepatic lobe.
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巨大肾细胞癌的肝脏浸润:诊断与管理之谜
肾细胞癌(RCC)是泌尿系统最致命的恶性肿瘤。RCC 侵犯肝右叶的情况非常罕见,是治疗上的一大挑战。有人建议同时进行肾切除术和右肝切除术,作为多模式治疗方法的一部分。我们在此讨论一位因右肾巨大 RCC 并浸润肝右叶而同时接受肾切除术和右肝切除术以及单次腹膜转移切除术的患者。一名 30 岁女性被诊断为右肾肿瘤侵犯右肝叶。多学科肿瘤委员会会议后,她被计划接受手术治疗。术中发现一个腹膜结节,冰冻切片显示恶性肿瘤阳性。考虑到患者年龄小、表现良好以及少转移性疾病,最终为她实施了右肾切除术和右肝切除术。她在术后第 6 天顺利出院。这种类型的RCC很少见,对于这种侵犯右肝叶的巨大RCC,联合肾切除术和右肝切除术是安全可行的。
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