Clinico-Laboratory Profile And Drug Sensitivity Pattern In Urinary Tract Infection Of Children In A Tertiary Care Hospital

Muhammad Bilal, Muhammad Tariq Nadeem, Adnan, Abdul Jalal, Ishfaq Ahmad, Abdul Samad
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Abstract

Background: Any component of the urinary system can get infected with bacteria, which is known as a urinary tract infection (UTI). It is one of the most common bacterial diseases in children. The study's objectives included identifying the clinical symptoms of UTI in children between the ages of one month and fifteen, as well as the bacteria responsible for the illness and their sensitivity to various medicines.Methods: This cross-sectional study was conducted at the CMH Rawalpindi, Pakistan, from January to June of 2022. Our analysis comprised 137 strongly suspected instances of UTI in children (1 month to 15 years old).Results: A total of 137 urine samples from paediatric patients suspected of having UTI were obtained in which the 93 samples (67.88%) generated significant bacteria. The two most common clinical symptoms of UTI patients in our research were fever and dysuria. E. coli was the most prevalent isolate in cases with paediatric UTI. Ampicillin, cephalosporins, and co-trimoxazole were the medications that were most effective against E. coli and Klebsiella, respectively.Conclusions: The age range between 1 and 5 years old was the one most usually affected by UTI. We must be aware of the need of doing a urine culture sensitivity test before to starting antimicrobial medicine in order to detect UTI early, avoid recurrent UTI, and reduce paediatric morbidity and mortality.
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一家三级医院儿童尿路感染的临床-实验室概况和药物敏感性模式
背景:泌尿系统的任何部位都可能受到细菌感染,这就是所谓的尿路感染(UTI)。它是儿童最常见的细菌性疾病之一。研究目的包括确定一个月至 15 岁儿童尿路感染的临床症状、致病细菌及其对各种药物的敏感性:这项横断面研究于 2022 年 1 月至 6 月在巴基斯坦拉瓦尔品第 CMH 进行。我们的分析包括 137 例强烈怀疑患尿毒症的儿童(1 个月至 15 岁):结果:我们共采集了 137 份疑似尿毒症儿童患者的尿液样本,其中 93 份样本(67.88%)产生了大量细菌。在我们的研究中,尿毒症患者最常见的两个临床症状是发烧和排尿困难。大肠杆菌是儿科 UTI 病例中最常见的分离菌。氨苄西林、头孢菌素和复方新诺明分别是对大肠杆菌和克雷伯氏菌最有效的药物:结论:1 至 5 岁的儿童是尿毒症的高发年龄段。我们必须意识到,在开始使用抗菌药物之前,有必要进行尿液培养敏感性检测,以便及早发现UTI,避免UTI反复发作,降低儿科发病率和死亡率。
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24 weeks
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