Hematological Parameters and Liver Function After COVID-19 Vaccination ( Simple Population Patients in Ramadi City – Iraq)

Ridhab Ajeel Jasim, Saif Subhi Noori, Adeeb Shakir Mahmood, Asmaa Jumaa, Fatin Zuher Abd Alkareem
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Abstract

This study aimed to investigate the influence of COVID-19 vaccination on liver function and blood parameters, specifically Mean Corpuscular Volume (MCV) and Hemoglobin (HGB) levels, among young adults (aged 18-32) in Anbar province. Blood samples from 50 individuals were collected at Ramadi Teaching Hospital, with half of the participants vaccinated and the other half unvaccinated. Results revealed a significant decrease in MCV and HGB levels among the vaccinated group compared to the unvaccinated group. Concurrently, liver function indicators, including Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), and Bilirubin, showed a marked increase in the vaccinated individuals, indicating potential hematological disorders and liver injury. These findings underscore the importance of COVID-19 vaccination while highlighting the need for continued monitoring of liver health and blood parameters in vaccinated individuals to mitigate potential long-term health implications. Highlights:  COVID-19 vaccination in young adults may lead to a significant decrease in Mean Corpuscular Volume (MCV) and Hemoglobin (HGB) levels. Liver function indicators such as Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), and Bilirubin exhibit a notable increase in vaccinated individuals. Continuous monitoring of liver health and blood parameters is crucial for assessing potential long-term health implications associated with COVID-19 vaccination. Keywords: COVID-19 Vaccination, Liver Function, Blood Parameters, Young Adults, Anbar Province.
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接种 COVID-19 疫苗后的血液参数和肝功能(伊拉克拉马迪市的普通人群患者)
本研究旨在调查接种 COVID-19 疫苗对安巴尔省年轻成年人(18-32 岁)肝功能和血液参数(尤其是平均体液容积 (MCV) 和血红蛋白 (HGB) 水平)的影响。我们在拉马迪教学医院采集了 50 人的血样,其中一半人接种了疫苗,另一半人未接种疫苗。结果显示,与未接种疫苗组相比,接种疫苗组的 MCV 和 HGB 水平明显下降。同时,接种疫苗者的肝功能指标(包括丙氨酸氨基转移酶(ALT)、碱性磷酸酶(ALP)和胆红素)明显升高,表明可能存在血液病和肝损伤。这些发现强调了接种 COVID-19 疫苗的重要性,同时也突出了持续监测接种者肝脏健康和血液参数的必要性,以减轻潜在的长期健康影响。 亮点: 青壮年接种 COVID-19 疫苗可能会导致平均体液容积 (MCV) 和血红蛋白 (HGB) 水平显著下降。 接种者的丙氨酸氨基转移酶 (ALT)、碱性磷酸酶 (ALP) 和胆红素等肝功能指标会明显升高。 持续监测肝脏健康和血液参数对于评估接种 COVID-19 疫苗对健康的潜在长期影响至关重要。 关键词COVID-19疫苗接种 肝功能 血液参数 年轻成年人 安巴尔省
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