Poster (Knowledge Generation) ID 1969160

IF 2.4 Q1 REHABILITATION Topics in Spinal Cord Injury Rehabilitation Pub Date : 2023-09-01 DOI:10.46292/sci23-1969160s
Julio C Furlan, E. Loh, M. Boulos
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Abstract

This ongoing cross-sectional study aims to examine the potential association between moderate-to-severe sleep apnea and severe cardiovascular dysfunction after spinal cord injury (SCI). This cross-sectional study included participants who were newly diagnosed with sleep apnea using a home-based/hospital unattended sleep screening test that quantifies the apnea-hypopnea index (AHI). Episodes of AD were defined as a sudden increase in systolic blood pressure (BP) of at least 20 mmHg. We exclude episodes of AD during sleep that were caused by triggers other than apnea or hypopnea. This study included English-speaking adults with subacute or chronic (≥1 month after SCI onset), cervical or high-thoracic (T6 or more cranial), complete or incomplete SCI, who reported clinical symptoms and/or signs suggestive of sleep apnea. This study included 45 individuals (14 females and 31 males; age range: 20 to 84 years, mean age: 57.0 years) with motor complete (n=22) or incomplete SCI at cervical (n=38) or high thoracic levels. Time since SCI varied from 1.5 months to 52 years. Their mean apnea-hypopnea index (AHI) was 16.0 events/hour (AHI range: 0.8 to 51.7 events/hour). Higher AHI was significantly correlated with more frequent silent episodes of AD (Rsqr=0.220, p=0.001) during sleep. The AHI was not associated with systolic BP (p=0.903), diastolic BP (p=0.639), mean arterial pressure (p=0.714), and heart rate (p=0.669) during sleep. The results of this cross-sectional study suggest that more severe sleep apnea is associated with frequent silent episodes of AD during sleep among individuals living with cervical or high-thoracic SCI.
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海报(知识生成)ID 1969160
这项正在进行的横断面研究旨在探讨中重度睡眠呼吸暂停与脊髓损伤(SCI)后严重心血管功能障碍之间的潜在关联。 这项横断面研究纳入了通过家庭/医院无人值守睡眠筛查测试新诊断出患有睡眠呼吸暂停的参与者,该测试可量化呼吸暂停-低通气指数(AHI)。AD发作的定义是收缩压(BP)突然升高至少20毫米汞柱。我们排除了睡眠中因呼吸暂停或低通气以外的诱因引起的急性呼吸暂停发作。 本研究纳入了亚急性或慢性(SCI 发病后≥1 个月)、颈椎或高胸椎(T6 或以上颅骨)、完全或不完全 SCI 的英语成年人,他们报告了提示睡眠呼吸暂停的临床症状和/或体征。 本研究共纳入 45 名患者(14 名女性和 31 名男性;年龄范围:20 至 84 岁,平均年龄:57.0 岁),他们均患有颈椎(38 名)或胸椎高位运动性完全(22 名)或不完全 SCI。SCI 后的时间从 1.5 个月到 52 年不等。他们的平均呼吸暂停-低通气指数(AHI)为 16.0 次/小时(AHI 范围:0.8 至 51.7 次/小时)。较高的 AHI 与睡眠中更频繁的无声 AD 发作有明显相关性(Rsqr=0.220,p=0.001)。AHI 与睡眠期间的收缩压(P=0.903)、舒张压(P=0.639)、平均动脉压(P=0.714)和心率(P=0.669)均无关联。 这项横断面研究的结果表明,在患有颈椎或高胸椎 SCI 的患者中,更严重的睡眠呼吸暂停与睡眠中频繁的无声 AD 发作有关。
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来源期刊
CiteScore
3.20
自引率
3.40%
发文量
33
期刊介绍: Now in our 22nd year as the leading interdisciplinary journal of SCI rehabilitation techniques and care. TSCIR is peer-reviewed, practical, and features one key topic per issue. Published topics include: mobility, sexuality, genitourinary, functional assessment, skin care, psychosocial, high tetraplegia, physical activity, pediatric, FES, sci/tbi, electronic medicine, orthotics, secondary conditions, research, aging, legal issues, women & sci, pain, environmental effects, life care planning
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