Relationship Between Anti-Mullerian Hormone and Demographic or Obstetric Features in Infertile Women, in Rasht, North of Iran

Roya Kaboodmehri, S. Sharami, Sodabeh Kazemi, Mandana Mansour Ghanaei, S. F. Dalil Heirati, Zahra Pourhabibi, Sina Montazeri
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Abstract

10.30699/jogcr.8.4.350 Background & Objective: Anti Mullerian hormone (AMH) level is a practical index of ovarian reserve and an indicator of ovarian response in infertile women. The aim of this study was to evaluate the relationship between AMH levels and demographic factors. Materials & Methods: In this cross-sectional study, conducted in Al-Zahra hospital Rasht in the north of Iran, 234 patients, 18-45 years old, were enrolled. The demographic parameters (e.g. age, education, habitat and etc.) and AMH levels were recorded for each patient. The patients were divided into two groups based on their AMH levels [group 1: less than 1.1 (ng/ml) vs. group 2: more than (1.1 ng/ml)]. The data was analyzed by SPSS-21 software. Results: The mean AMH level was 2.66 ng/ml. Age, education status and habitat showed significant differences among subjects with AMH levels, so that with aging the AMH levels decreased. Patients living in villages or the ones with low educational degrees and those with higher parities also revealed lower levels of AMH (p<0.05). Conclusion: There was a significant relationship between age, educational status and habitat with AMH values. Similar to other studies, we believe that with aging the AMH levels decrease. Furthermore, the other two aforementioned demographic features could affect a woman’s ovarian reserve and fertility status, too.
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伊朗北部拉什特不育妇女体内抗穆勒里激素与人口学或产科特征之间的关系
10.30699/jogcr.8.4.350 背景与目的:抗苗勒氏管激素(AMH)水平是不孕妇女卵巢储备的实用指标,也是卵巢反应的指标。本研究旨在评估 AMH 水平与人口统计学因素之间的关系。材料与方法:这项横断面研究在伊朗北部拉什特的扎赫拉医院(Al-Zahra hospital Rasht)进行,共招募了 234 名 18-45 岁的患者。记录了每位患者的人口统计学参数(如年龄、教育程度、居住地等)和 AMH 水平。根据 AMH 水平将患者分为两组[第 1 组:低于 1.1(纳克/毫升);第 2 组:高于(1.1 纳克/毫升)]。数据采用 SPSS-21 软件进行分析。结果平均 AMH 水平为 2.66 纳克/毫升。年龄、教育状况和居住地在 AMH 水平上存在显著差异,因此随着年龄的增长,AMH 水平会下降。居住在乡村或教育程度低的患者以及准妈妈人数较多的患者的 AMH 水平也较低(P<0.05)。结论年龄、教育程度和居住地与 AMH 值之间存在明显关系。与其他研究相似,我们认为随着年龄的增长,AMH 水平会下降。此外,上述其他两个人口特征也会影响妇女的卵巢储备和生育状况。
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