FRACTIONAL MATHEMATICAL MODEL OF HIV AND CD4+ T-CELLS INTERACTIONS WITH HAART TREATMENT

Abstract

. This study provides the mathematical model of the interaction between the HIV and CD4+ T cells. This research develops other research by formulating a model with the fractional Caputo derivative approach with fractional order α. Based on the model, we obtain the equilibrium point and analyze the stability criterion of the equilibrium point. Furthermore, we perform the Next Generation Matrix method to calculate the basic reproduction number (𝑅 0 ) . Then, we apply the Grunwald-Letnikov Explicit method to show the numerical result of the model. The result of this study could assist for future improvement, especially for fractional modelling.