Nanosponge: An Overview

Poonam Raut, Nikita Bhosale, Varda Joshi
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Abstract

The "Pharmaceutical Nanotechnology" subfield of pharmaceutical sciences, which is now in its infancy, offers new tools, prospects, and horizons with potential applications in the field of therapy and diagnostics of disease. Pharmaceutical nanotechnology consists of items that are nanosized and may be altered in many ways to enhance their properties. According to the administration method, the nanoporous particles are NSs that may entangle a wide variety of materials before being absorbed into a suitable formulation. They delay the drug's release in a regulated manner, stop the drug's protein from degrading, and disperse the drug where it is needed. They can move about the body, connect to the skin, and release the medicine at the intended target spot in a regulated and predictable way. They have excellent aqueous solubility, making them a carrier for medications with poor water solubility. When compared to other nanocarriers, they have greater drug loading capabilities. They are therefore appropriate for addressing issues with active ingredient stability, solubility, and delayed release. The main benefit of nanosponges of weakly water soluble medicines. They can function as biocatalysts in the administration of enzymes, proteins, vaccines, and antibodies and can administer medications via a variety of routes, including oral, topical, parental, etc.
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纳米海绵概述
医药科学的 "医药纳米技术 "子领域目前正处于起步阶段,它为疾病治疗和诊断领域的潜在应用提供了新的工具、前景和视野。医药纳米技术包括纳米尺寸的物品,可通过多种方式改变它们的尺寸以增强其特性。根据给药方法,纳米多孔颗粒是一种 NSs,在被吸收到合适的制剂中之前,可以缠绕各种材料。它们以可调节的方式延迟药物释放,阻止药物蛋白质降解,并将药物分散到需要的地方。它们可以在体内移动,与皮肤连接,并以可调节、可预测的方式将药物释放到预定的靶点。它们具有出色的水溶性,因此可作为水溶性较差药物的载体。与其他纳米载体相比,它们具有更强的药物负载能力。因此,它们适用于解决活性成分稳定性、溶解性和延迟释放等问题。纳米海绵对弱水溶性药物的主要益处。它们可以在施用酶、蛋白质、疫苗和抗体时发挥生物催化剂的作用,并可通过口服、局部外用、亲子等多种途径施用药物。
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