Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management

IF 3.8 3区医学 Q1 MEDICINE, GENERAL & INTERNAL Dm Disease-A-Month Pub Date : 2024-01-01 DOI:10.1016/j.disamonth.2023.101674

Zara Manuelyan MD , Edward Butt MD, MPH , Sreeram Parupudi MD

引用次数: 0

Abstract

Behçet's disease (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the GI tract. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based on clinical criteria. Management of intestinal BD includes different classes of medications including corticosteroids, 5-aminosalicylic acid, immunomodulators, and anti-tumor necrosis factor alpha monoclonal antibody agents. In this review, we aim to focus on intestinal BD and provide details of clinical manifestations, diagnosis and therapeutic options of intestinal BD from gastroenterology viewpoint.

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消化道白塞氏病：表现、诊断和管理

贝赫切特病（BD）是一种罕见的炎症性血管疾病，具有复发性口腔和生殖器口疮溃疡，以及眼部和皮肤表现。胃肠道（BD）可累及消化道的任何部位。不过，这种疾病通常发生在回肠末端，其次是回盲部。由于缺乏病理诊断测试，诊断具有挑战性；因此，诊断要以临床标准为基础。肠道 BD 的治疗包括不同类别的药物，包括皮质类固醇、5-氨基水杨酸、免疫调节剂和抗肿瘤坏死因子 alpha 单克隆抗体药物。在这篇综述中，我们将重点关注肠道 BD，并从消化内科的角度详细介绍肠道 BD 的临床表现、诊断和治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dm Disease-A-Month 医学-医学：内科

CiteScore

5.70

自引率

2.50%

发文量

140

审稿时长

>12 weeks

期刊介绍： Designed for primary care physicians, each issue of Disease-a-Month presents an in-depth review of a single topic. In this way, the publication can cover all aspects of the topic - pathophysiology, clinical features of the disease or condition, diagnostic techniques, therapeutic approaches, and prognosis.