Fibrinogen as a potential diagnostic marker for prediction and evaluation of postpartum hemorrhage: a retrospective study.

IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Journal of Maternal-Fetal & Neonatal Medicine Pub Date : 2024-12-01 Epub Date: 2024-01-07 DOI:10.1080/14767058.2023.2300418
Yanke Zou, Yixiao Jiang, Dawei Zhu, Ling Liu, Xiuhui Zheng, Xing Gu, Changxiao Huang, Li Li
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引用次数: 0

Abstract

Objective: To investigate whether prenatal fibrinogen (FIB) or other related factors could be utilized to evaluate the risk of postpartum hemorrhage (PPH).

Methods: A retrospective study was conducted in a database from January 2015 to December 2019. A total of 128 patients were enrolled and evaluated with FIB, in which 55 patients were assigned to low FIB and 73 in normal FIB.

Results: According to the volume of blood loss, the mean of the low FIB group (<4 g/L) was markedly higher than that of the normal FIB group (≥4 g/L). Prenatal FIB was negatively correlated with PPH volume. The receiver operating characteristic (ROC) curve results indicated that the value of prenatal FIB was 0.701 to predict refractory PPH.

Conclusions: Prenatal FIB was significantly related to thrombin time (TT), which may be an independent factor to predict the coagulation state of prenatal pregnancy.

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纤维蛋白原作为预测和评估产后出血的潜在诊断标志物:一项回顾性研究。
目的研究是否可以利用产前纤维蛋白原(FIB)或其他相关因素来评估产后出血(PPH)的风险:在2015年1月至2019年12月的数据库中进行了一项回顾性研究。共有128名患者入选并接受了FIB评估,其中55名患者被分配到低FIB,73名患者被分配到正常FIB:根据失血量,低FIB组的平均值(结论:产前 FIB 与凝血酶时间(TT)明显相关,这可能是预测产前妊娠凝血状态的一个独立因素。
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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
217
审稿时长
2-3 weeks
期刊介绍: The official journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies and The International Society of Perinatal Obstetricians. The journal publishes a wide range of peer-reviewed research on the obstetric, medical, genetic, mental health and surgical complications of pregnancy and their effects on the mother, fetus and neonate. Research on audit, evaluation and clinical care in maternal-fetal and perinatal medicine is also featured.
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