Severe esophagitis induced by antituberculosis drugs: a case report

Roxana Flores Mamani, Franciele Moreira Silva, Marcos Vidal de Lima-Júnior, Juliana Paitach de Oliveira Lima, Vitor Montez Vianna, Rivelino Trindade de Azevedo, B. McBenedict, E. Martins
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Abstract

ABSTRACT Tuberculosis stands as one of humanity’s oldest afflictions, intrinsically intertwined with social disparities. This formidable disease spares no age group and remains the prevailing cause of infection-induced mortality worldwide, particularly in developing nations. We present a case of a 56-year-old woman with diabetes who was diagnosed with Pulmonary Tuberculosis. After receiving antituberculosis drugs as part of her treatment, she experienced a range of systemic manifestations and suffered from severe ulcerative esophagitis. This adverse reaction led to uncontrollable gastrointestinal intolerance, tragically resulting in her untimely demise. The incident underscores the potential seriousness of adverse reactions that can arise from tuberculosis treatment medications.
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抗结核药物诱发的严重食管炎:一份病例报告
摘要 结核病是人类最古老的疾病之一,与社会差距密切相关。这种可怕的疾病不分年龄段,仍然是全世界,尤其是发展中国家感染致死的主要原因。我们介绍了一例 56 岁女性糖尿病患者被诊断为肺结核的病例。在接受抗结核药物治疗后,她出现了一系列全身症状,并患上了严重的溃疡性食管炎。这种不良反应导致了无法控制的肠胃不适,不幸导致她过早死亡。这一事件凸显了结核病治疗药物可能引起的不良反应的潜在严重性。
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