Treating Hepatitis C Virus Infection in Jails as an Offset to Declines in Treatment Activity in the Community, New York City, NY, 2014–2020

Justin Chan MD , Matthew J. Akiyama MD , Emily Julian RN , Rodrigue Joseph MD , Wendy McGahee MD , Zachary Rosner MD , Patricia Yang DrPH , Ross MacDonald MD
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Abstract

Introduction

There are scant data on implementation of large-scale direct-acting antiviral treatment for hepatitis C virus in jails in the U.S. New York City Health + Hospitals/Correctional Health Services aimed to scale up hepatitis C virus treatment in the New York City jail system. This study describes the trends in annual hepatitis C virus treatment in New York City jails compared with those in Medicaid-funded treatment in the New York City community from 2014 to 2020.

Methods

In this observational study, we extracted annual counts of direct-acting antiviral prescriptions for hepatitis C virus for those (1) in the New York City community who were covered by Medicaid and (2) those detained in New York City jails for 2014–2020. Data sources were New York City Department of Health and Mental Hygiene annual reports and Correctional Health Services treatment records, respectively. We used linear regression analysis to test for significant trends in annual treatment in these 2 cohorts during 2015–2019.

Results

From 2015 to 2019, treatments started in New York City jails increased annually (p=0.001), whereas Medicaid-funded prescriptions in the New York City community declined since a peak in 2015 (p<0.001). In 2019, New York City jail-based treatment initiations totaled the equivalent of 10% of treatment covered by Medicaid in New York City, up from 0.3% in 2015.

Conclusions

Scale up of jail-based hepatitis C virus treatment is an important strategy to offset declines observed in the community. Addressing barriers to care in jail, such as improving testing, linkage to care, and affordability of direct-acting antivirals for jail-based health services, can help sustain high levels of treatment in U.S. jails and other carceral facilities.

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2014-2020 年在监狱治疗丙型肝炎病毒感染以抵消社区治疗活动的减少,纽约州纽约市
导言美国监狱大规模实施丙型肝炎病毒直接作用抗病毒治疗的数据很少。本研究描述了从 2014 年到 2020 年期间,纽约市监狱与纽约市社区中接受医疗补助资助治疗的丙型肝炎病毒年度治疗趋势。方法在这项观察性研究中,我们提取了 2014-2020 年期间,(1) 纽约市社区中接受医疗补助的丙型肝炎病毒直接作用抗病毒药物处方的年度计数;(2) 纽约市监狱中被拘留的丙型肝炎病毒直接作用抗病毒药物处方的年度计数。数据来源分别是纽约市健康与心理卫生局的年度报告和惩教健康服务机构的治疗记录。我们使用线性回归分析来检验 2015-2019 年期间这 2 个队列中年度治疗的显著趋势。结果从 2015 年到 2019 年,纽约市监狱中开始的治疗逐年增加(p=0.001),而纽约市社区中医疗补助资助的处方自 2015 年达到峰值后有所下降(p<0.001)。2019年,纽约市监狱启动的治疗总计相当于纽约市医疗补助计划所覆盖治疗的10%,高于2015年的0.3%。结论扩大监狱丙型肝炎病毒治疗是抵消在社区观察到的下降趋势的重要策略。解决监狱中的治疗障碍,如改善检测、治疗链接以及监狱医疗服务机构对直接作用抗病毒药物的可负担性,有助于维持美国监狱和其他囚禁设施的高水平治疗。
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AJPM focus
AJPM focus Health, Public Health and Health Policy
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