Malignant melanoma of gastrointestinal tract on 18F-FDG PET/CT: three case reports.

IF 2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING American journal of nuclear medicine and molecular imaging Pub Date : 2023-12-25 eCollection Date: 2023-01-01
Wenpeng Huang, Yongkang Qiu, Xiaoyan Xiao, Liming Li, Qi Yang, Jianbo Gao, Lei Kang
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Abstract

Primary malignant melanoma most frequently occurs in the skin. Melanoma affecting the gastrointestinal (GI) tract has been substantiated for lesions occurring in the esophagus, stomach, small bowel, and anorectum through multiple published reports, given the presence of melanocytes in these areas. Nevertheless, owing to the exceedingly low incidence of this disease, reports on its clinical features are few, and treatment approaches lack standardization. In this study, we present three cases of GI melanoma with imaging manifestations, emphasizing the pivotal role of 18F-FDG PET/CT in staging for GI melanoma. Establishing a definitive diagnosis of primary GI melanoma necessitates the exclusion of the possibility of metastasis from more prevalent primary sites. Advancements in molecular imaging technologies and the development of novel tracers provided significant promising methods for enhancing the diagnosis and management of melanoma, contributing to improved patient outcomes and overall disease management.

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18F-FDG PET/CT 胃肠道恶性黑色素瘤:三份病例报告。
原发性恶性黑色素瘤最常发生在皮肤上。由于食道、胃、小肠和肛门直肠等部位存在黑色素细胞,多篇已发表的报告证实,发生在这些部位的黑色素瘤会影响胃肠道。然而,由于这种疾病的发病率极低,有关其临床特征的报道也很少,治疗方法也缺乏标准化。在本研究中,我们介绍了三例有影像学表现的消化道黑色素瘤,强调了 18F-FDG PET/CT 在消化道黑色素瘤分期中的关键作用。要明确诊断原发性消化道黑色素瘤,就必须排除更常见的原发部位转移的可能性。分子成像技术的进步和新型示踪剂的开发为加强黑色素瘤的诊断和管理提供了大有可为的方法,有助于改善患者预后和整体疾病管理。
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来源期刊
American journal of nuclear medicine and molecular imaging
American journal of nuclear medicine and molecular imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
自引率
4.00%
发文量
4
期刊介绍: The scope of AJNMMI encompasses all areas of molecular imaging, including but not limited to: positron emission tomography (PET), single-photon emission computed tomography (SPECT), molecular magnetic resonance imaging, magnetic resonance spectroscopy, optical bioluminescence, optical fluorescence, targeted ultrasound, photoacoustic imaging, etc. AJNMMI welcomes original and review articles on both clinical investigation and preclinical research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.
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