PET/Computed Tomography Transformation of Oncology

IF 3 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING PET Clinics Pub Date : 2024-01-09 DOI:10.1016/j.cpet.2023.12.012

Alireza Ghodsi MD , Rodney J. Hicks MD, FRACP , Amir Iravani MD, FRACP

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正电子发射计算机断层扫描（PET/Computed Tomography）对肿瘤学的改造：免疫疗法评估。

免疫疗法改变了多种恶性肿瘤的治疗格局，并产生了较高的抗肿瘤反应。免疫疗法可能与新的反应和进展模式有关，这对传统的治疗反应评估标准（包括实体瘤反应评估标准（RECIST）1.1）提出了巨大挑战。除了计算机断层扫描（CT）和核磁共振成像（MRI）提供的形态学细节外，混合分子成像作为一种全面的成像模式出现了，它有能力探究葡萄糖代谢等病理生理机制。本综述重点介绍了 2-脱氧-2-[18F]氟-D-葡萄糖正电子发射断层扫描/计算机断层扫描（18F-FDG PET/CT）在预后判断、反应监测和识别免疫相关不良事件方面的现状。此外，该研究还探讨了新型免疫 PET 示踪剂的潜在作用，这些示踪剂可通过对免疫治疗策略所涉及的特定途径进行成像来补充 18F-FDG PET/CT 的使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PET Clinics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

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5.70

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3.80%

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期刊介绍： As the clinical applications of positron emission tomography (PET) increase, the new PET Clinics brings together the combined expertise of leading authorities in the field to provide you incisive clinical reviews on advances in the use of PET and combined PET/CT. Published quarterly, PET Clinics provides concise, practical guidance on the clinical issues you face every day. It examines PET is effectiveness in cancer diagnosis and staging, as well as exploring PET is usefulness in the areas of dementia, myocardial viability, and other conditions. Full-color images featured throughout. Topics covered include Breast Cancer, Alzheimer is Disease and Dementia, Lymphoma, Lung Cancer, Cardiology, Pediatric Applications, Infection and Inflammation.

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