WITHDRAWN: Wheatgrass (Triticum aestivum) Extract Loaded Chitosan Solid Lipid Nanoparticles: Formulation, Physicochemical Characterisation and Cytotoxic Potential

IF 3.1 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Recent Patents on Nanotechnology Pub Date : 2024-01-10 DOI:10.2174/0118722105270861231128081639
Neha Minocha, Parijat Pandey, Nidhi Sharma, Sangita Saini
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Abstract

Since the content of the article shows a high degree of similarity to a previously published work by the same group of authors, the article has been withdrawn from the journal Recent Patents on Nanotechnology with the consent of the Editor-in-Chief.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policiesmain.php

Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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小麦草(Triticum Aestivum)提取物负载壳聚糖固体脂质纳米颗粒:配方、理化特性和细胞毒性潜力。
背景:癌症在全世界都很普遍,被认为是一种多种多样的疾病。世界上最常见的癌症原因之一是氧化应激,而这可以通过服用任何形式的草本植物小麦草来克服:本研究的目的是采用 Box-Behnken 设计法配制小麦草提取物负载固体脂质纳米粒子,并研究配方变量的影响:方法:本工作计划采用热均质法,通过盒-贝肯设计法研制小麦草填充壳聚糖固体脂质纳米粒子。本研究探讨了海藻酸钠浓度、壳聚糖浓度和超声时间这三个配方变量对粒度和夹持效率的影响。小麦草的提取是在索氏提取器中进行的,使用的是甲醇提取物。此外,作者还研究了与小麦草相关的最新专利,以加深对这种草本植物的理解:结果:采用热均质化技术制备了含有固体脂质纳米颗粒(SLNs)的小麦提取物。对 BBD 的所有配方进行了粒度分析,粒度范围为 394.4 至 911.2 nm,多分散指数范围为 0.527 至 1.0。通过使用海藻酸钠作为表面稳定剂,在超声时间 ~ 10 分钟的条件下,发现批号 BB SLN-8 是最合适的,因为其最大负载能力为 58.23 ±0.11 %(重量比),最大夹带效率为 55.12 ±0.17 %(重量比),最小粒径为 394.4 nm,最大产率为 49.87%。在特性研究和 MCF-6 细胞系研究中发现,小麦草具有抗氧化潜力,对乳腺癌有特效:结论:作为一种治疗癌症的替代药物,小麦草因其抗氧化剂含量高而被认为是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Recent Patents on Nanotechnology
Recent Patents on Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
CiteScore
4.70
自引率
10.00%
发文量
50
审稿时长
3 months
期刊介绍: Recent Patents on Nanotechnology publishes full-length/mini reviews and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of nanotechnology. A selection of important and recent patents on nanotechnology is also included in the journal. The journal is essential reading for all researchers involved in nanotechnology.
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