[Experimental chronic stomach ulcer].

W Brandt, P Buntrock
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Abstract

A survey of different methods for the production of experimental gastric ulcer in rats is given. 20 male Wistarrats got a chronic gastric ulcer after the injection of 0.05 ml acetic acid (30%) under the serosa. We documented the developing of the ulcer in phases by means of histology. In contrast to other models the Acetic Acid Injection Ulcer (by Takagi et al. 1969) shows similar histology and chronicity to human histology and chronicity.

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实验性慢性胃溃疡。
对大鼠实验性胃溃疡的不同制备方法进行了综述。20只雄性wistar大鼠在浆膜下注射0.05 ml(30%)醋酸后出现慢性胃溃疡。我们用组织学方法记录了溃疡的分期发展。与其他模型相比,醋酸注射溃疡(Takagi et al. 1969)表现出与人类相似的组织学和慢性性。
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