Mathematical Modeling for a CHIKV Transmission Under the Influence of Periodic Environment

M. El Hajji, N. S. Alharbi, Mohammed H. Alharbi
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Abstract

We studied a simple mathematical model for the chikungunya virus (CHIKV) spread under the influence of a seasonal environment with two routes of infection. We investigated the existence and the uniqueness of a bounded positive solution, and we showed that the system admits a global attractor set. We calculated the basic reproduction number R0 for the both cases, the fixed and seasonal environment which permits us to characterise both, the extinction and the persistence of the disease with regard to the values of R0. We proved that the virus-free equilibrium point is globally asymptotically stable if R0≤1, while the disease will persist if R0>1. Finally, we gave some numerical examples confirming the theoretical findings.
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周期性环境影响下 CHIKV 传播的数学建模
我们研究了基孔肯雅病毒(CHIKV)在两种感染途径的季节性环境影响下传播的简单数学模型。我们研究了有界正解的存在性和唯一性,并证明该系统存在一个全局吸引子集。我们计算了固定环境和季节环境两种情况下的基本繁殖数 R0,这使我们能够根据 R0 的值来描述疾病的消亡和持续。我们证明,如果 R0≤1 ,无病毒平衡点在全局上是渐近稳定的,而如果 R0>1 ,疾病将持续存在。最后,我们给出了一些数值示例,证实了理论结论。
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来源期刊
CiteScore
1.30
自引率
10.00%
发文量
60
审稿时长
12 weeks
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