Functional proteomics based on protein microarray technology for biomedical research.

3区 生物学 Q1 Biochemistry, Genetics and Molecular Biology Advances in protein chemistry and structural biology Pub Date : 2024-01-01 Epub Date: 2023-05-15 DOI:10.1016/bs.apcsb.2023.04.002
Pablo Juanes-Velasco, Carlota Arias-Hidalgo, Alicia Landeira-Viñuela, Ana Nuño-Soriano, Marina Fuentes-Vacas, Rafa Góngora, Ángela-Patricia Hernández, Manuel Fuentes
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Abstract

This chapter traces a route through Proteomics from its origins to the present day. The different proteomics applications are discussed with a focus on microarray technology. Analytical microarrays, functional microarrays and reverse phase microarrays and their different applications are discussed. Several studies are mentioned where the great versatility of this approach is shown. Finally, the advantages and future challenges of microarray technology are outlined.

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基于蛋白质微阵列技术的功能蛋白质组学用于生物医学研究。
本章回顾了蛋白质组学从起源到今天的发展历程。本章以芯片技术为重点,讨论了不同的蛋白质组学应用。讨论了分析芯片、功能芯片和反相芯片及其不同的应用。还提到了几项研究,这些研究显示了这种方法的巨大多功能性。最后,概述了微阵列技术的优势和未来挑战。
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来源期刊
Advances in protein chemistry and structural biology
Advances in protein chemistry and structural biology BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
7.40
自引率
0.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Published continuously since 1944, The Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.
期刊最新文献
In silico network pharmacology study on Glycyrrhiza glabra: Analyzing the immune-boosting phytochemical properties of Siddha medicinal plant against COVID-19. A computational pipeline elucidating functions of conserved hypothetical Trypanosoma cruzi proteins based on public proteomic data. Analysis of endoglucanases production using metatranscriptomics and proteomics approach. Application of functional proteomics in understanding RNA virus-mediated infection. Functional proteomics based on protein microarray technology for biomedical research.
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