Phage therapy: resurrecting a historical solution for the contemporary challenge of rising antibiotic resistance in Latin America.

IF 4.2 2区 医学 Q1 INFECTIOUS DISEASES Expert Review of Anti-infective Therapy Pub Date : 2024-01-01 Epub Date: 2024-02-12 DOI:10.1080/14787210.2024.2305842
Justin Yeager, Ana María Gómez-Jaramillo, Esteban Ortiz-Prado, Manuel Calvopiña, Benjamin K Chan
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Abstract

Introduction: Antimicrobial resistance in Latin America is a growing concern in both human and non-human animal populations. The economic burden that is likely to be imposed through increased resistance will cause further strains on public health systems and the population at large.

Areas covered: We propose the rapid adoption and implementation of phage therapy as a necessary addition to the medical arsenal to help mitigate antimicrobial resistance, with an emphasis on considering the potential benefits that highly biodiverse countries such as Ecuador may have on phage discovery. However, programs may count on limited government support and/or facilitation, which could slow progress.

Expert opinion: We highlight the need for educational campaigns to be implemented in parallel with the development of phage therapy programs, particularly to implement these novel treatments in rural and indigenous communities.

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噬菌体疗法:复活历史解决方案,应对拉丁美洲抗生素耐药性上升的当代挑战。
导言:在拉丁美洲,人类和非人类动物对抗生素的耐药性日益令人担忧。抗药性增加可能带来的经济负担将进一步加重公共卫生系统和广大民众的负担:我们建议迅速采用和实施噬菌体疗法,将其作为医疗武库的必要补充,以帮助减轻抗菌药耐药性,重点考虑厄瓜多尔等生物多样性高度丰富的国家在噬菌体发现方面可能带来的潜在益处。然而,该计划可能会依赖于有限的政府支持和/或促进,这可能会减缓进展:我们强调,在制定噬菌体疗法计划的同时,有必要开展教育活动,尤其是在农村和土著社区实施这些新型疗法。
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来源期刊
CiteScore
11.20
自引率
0.00%
发文量
66
审稿时长
4-8 weeks
期刊介绍: Expert Review of Anti-Infective Therapy (ISSN 1478-7210) provides expert reviews on therapeutics and diagnostics in the treatment of infectious disease. Coverage includes antibiotics, drug resistance, drug therapy, infectious disease medicine, antibacterial, antimicrobial, antifungal and antiviral approaches, and diagnostic tests.
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