Evaluation of Clinical Manifestations, Pattern of Involvement, and Surgical Outcomes in Patients with Post Covid-19 Head and Neck Mucormycosis Infection among Patients Admitted To Namazi Hospital, Shiraz, Iran (2021-2022).

IF 0.9 Q3 SURGERY World Journal of Plastic Surgery Pub Date : 2023-01-01 DOI:10.61186/wjps.12.3.64
Mehryar Nahaei, Gholamreza Motazedian, Ali-Akbar Mohammadi, Mohammad Ali Davarpanah, Parsa Yazdanpanahi, Nazanin Ayareh, Fateme Salari, Alireza Keshtkar
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Abstract

Background: COVID-19, caused by SARS-CoV-2, is a global pandemic that particularly affects immunocompromised individuals, leading to secondary bacterial and fungal infections. Mucormycosis, caused by Mucorales fungi, is a severe infection primarily affecting immunocompromised individuals. The COVID-19 pandemic has seen a surge in mucormycosis cases worldwide, with India experiencing a significant increase. Various factors, including diabetes mellitus, contribute to the risk of mucormycosis. This study investigated head and neck mucormycosis in patients with prior COVID-19 infection.

Methods: Data from 45 patients were analyzed, with diabetes being the most common risk factor. Visual symptoms, ethmoid bone involvement, and orbital bone involvement were also identified as significant factors.

Results: The COVID-19 pandemic has led to an increase in mucormycosis cases, particularly in the head and neck region, with high mortality. Successful management involves addressing underlying factors, surgical debridement, and antifungal therapy.

Conclusion: Timely debridement reduces morbidity and mortality.

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对伊朗设拉子市纳马济医院收治的 Covid-19 后头颈部黏菌血症感染患者的临床表现、感染模式和手术结果进行评估(2021-2022 年)。
背景:由 SARS-CoV-2 引起的 COVID-19 是一种全球性流行病,尤其影响免疫力低下的人群,导致继发性细菌和真菌感染。由真菌粘孢子菌引起的粘孢子菌病是一种严重感染,主要影响免疫力低下的人群。在 COVID-19 大流行期间,全球粘孢子菌病病例激增,印度的病例显著增加。包括糖尿病在内的各种因素都会增加患粘孢子菌病的风险。本研究调查了曾感染COVID-19的患者的头颈部粘孢子菌病:分析了 45 名患者的数据,其中糖尿病是最常见的风险因素。视觉症状、蝶骨受累和眼眶骨受累也被认为是重要因素:COVID-19大流行导致粘孢子菌病病例增加,尤其是头颈部地区,死亡率很高。成功的治疗包括解决潜在因素、手术清创和抗真菌治疗:结论:及时清创可降低发病率和死亡率。
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