From treatable traits to GETomics in airway disease: moving towards clinical practice

IF 9 1区 医学 Q1 RESPIRATORY SYSTEM European Respiratory Review Pub Date : 2024-01-17 DOI:10.1183/16000617.0143-2023
Alberto Papi, Rosa Faner, Ian Pavord, Federico Baraldi, Vanessa M. McDonald, Mike Thomas, Marc Miravitlles, Nicholas Roche, Alvar Agustí
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Abstract

The treatable traits approach represents a strategy for patient management. It is based on the identification of characteristics susceptible to treatments or predictive of treatment response in each individual patient. With the objective of accelerating progress in research and clinical practice relating to such a treatable traits approach, the Portraits event was convened in Barcelona, Spain, in November 2022. Here, while reporting the key concepts that emerged from the discussions during the meeting, we review the current state of the art related to treatable traits and chronic respiratory diseases management, and we describe the possible actions that clinicians can take in clinical practice to implement the treatable traits framework. Furthermore, we explore the new concept of GETomics and the new models of research in the field of COPD.

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从气道疾病的可治疗性状到 GETomics:走向临床实践
可治疗特征法是一种患者管理策略。它基于对每个患者易受治疗影响或可预测治疗反应的特征的识别。为了加快与这种可治疗特质方法相关的研究和临床实践的进展,2022 年 11 月在西班牙巴塞罗那举行了 "肖像 "活动。在此,我们在报告会议讨论中提出的关键概念的同时,回顾了与可治疗特质和慢性呼吸系统疾病管理相关的技术现状,并介绍了临床医生在临床实践中为实施可治疗特质框架而可能采取的行动。此外,我们还探讨了慢性阻塞性肺病领域的 GETomics 新概念和新研究模式。
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来源期刊
European Respiratory Review
European Respiratory Review Medicine-Pulmonary and Respiratory Medicine
CiteScore
14.40
自引率
1.30%
发文量
91
审稿时长
24 weeks
期刊介绍: The European Respiratory Review (ERR) is an open-access journal published by the European Respiratory Society (ERS), serving as a vital resource for respiratory professionals by delivering updates on medicine, science, and surgery in the field. ERR features state-of-the-art review articles, editorials, correspondence, and summaries of recent research findings and studies covering a wide range of topics including COPD, asthma, pulmonary hypertension, interstitial lung disease, lung cancer, tuberculosis, and pulmonary infections. Articles are published continuously and compiled into quarterly issues within a single annual volume.
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