Intramuscular botulinum toxin-A in complex regional pain syndrome resistant to standard treatment: a case report.

IF 1.9 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Wiener Klinische Wochenschrift Pub Date : 2024-07-01 Epub Date: 2024-01-19 DOI:10.1007/s00508-023-02317-x
Yasemin Tombak, Ozgur Zeliha Karaahmet, Ece Unlu Akyuz
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Abstract

Objective: To present a patient with complex regional pain syndrome type 1 (CRPS-I) and improvement of contracture of hand muscles and grip strength after successful treatment with botulinum neurotoxin‑A (BoNT-A).

Case: A 53-year-old woman with CRPS‑I experienced severe allodynia, swelling and autonomic changes in the left hand after a distal radius fracture. Over the succeeding months, she developed contracture of the left hand muscles which was treated with injection of BoNT‑A into the hand muscles (10 points).

Results: In the patient treatment with BoNT‑A an improvement was seen in the hand range of motion (ROM) and grip strength.

Conclusion: Successful results can be obtained with BoNT‑A injection in treatment-resistant CRPS‑I cases which may develop joint contracture.

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肌肉注射肉毒杆菌毒素-A 用于标准治疗无效的复杂性区域疼痛综合征:病例报告。
摘要介绍一名 1 型复杂性区域疼痛综合征(CRPS-I)患者在成功接受肉毒杆菌神经毒素-A(BoNT-A)治疗后,手部肌肉挛缩和握力得到改善的病例:一名 53 岁的 CRPS-I 女性患者在一次桡骨远端骨折后,左手出现了严重的异感、肿胀和自主神经变化。在随后的几个月里,她的左手肌肉出现挛缩,在手部肌肉注射 BoNT-A(10 点)后,她的左手肌肉得到了治疗:结果:接受 BoNT-A 治疗的患者手部活动范围(ROM)和握力均有所改善:结论:对于可能出现关节挛缩的耐药性 CRPS-I 病例,注射 BoNT-A 可获得成功的治疗效果。
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来源期刊
Wiener Klinische Wochenschrift
Wiener Klinische Wochenschrift 医学-医学:内科
CiteScore
4.70
自引率
3.80%
发文量
110
审稿时长
4-8 weeks
期刊介绍: The Wiener klinische Wochenschrift - The Central European Journal of Medicine - is an international scientific medical journal covering the entire spectrum of clinical medicine and related areas such as ethics in medicine, public health and the history of medicine. In addition to original articles, the Journal features editorials and leading articles on newly emerging topics, review articles, case reports and a broad range of special articles. Experimental material will be considered for publication if it is directly relevant to clinical medicine. The number of international contributions has been steadily increasing. Consequently, the international reputation of the journal has grown in the past several years. Founded in 1888, the Wiener klinische Wochenschrift - The Central European Journal of Medicine - is certainly one of the most prestigious medical journals in the world and takes pride in having been the first publisher of landmarks in medicine.
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