An automated cervical cancer diagnosis using genetic algorithm and CANFIS approaches.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.3233/THC-230926
Elayaraja P, Kumarganesh S, K Martin Sagayam, Andrew J
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引用次数: 0

Abstract

Background: Cervical malignancy is considered among the most perilous cancers affecting women in numerous East African and South Asian nations, both in terms of its prevalence and fatality rates.

Objective: This research aims to propose an efficient automated system for the segmentation of cancerous regions in cervical images.

Methods: The proposed techniques encompass preprocessing, feature extraction with an optimized feature set, classification, and segmentation. The original cervical image undergoes smoothing using the Gaussian Filter technique, followed by the extraction of Local Binary Pattern (LBP) and Grey Level Co-occurrence Matrix (GLCM) features from the enhanced cervical images. LBP features capture pixel relationships within a mask window, while GLCM features quantify energy metrics across all pixels in the images. These features serve to distinguish normal cervical images from abnormal ones. The extracted features are optimized using Genetic Algorithm (GA) as an optimization method, and the optimized sets of features are classified using the Co-Active Adaptive Neuro-Fuzzy Inference System (CANFIS) classification method. Subsequently, a morphological segmentation technique is employed to categorize irregular cervical images, identifying and segmenting malignant regions within them.

Results: The proposed approach achieved a sensitivity of 99.09%, specificity of 99.39%, and accuracy of 99.36%.

Conclusion: The proposed approach demonstrated superior performance compared to state-of-the-art techniques, and the results have been validated by expert radiologists.

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利用遗传算法和 CANFIS 方法自动诊断宫颈癌。
背景:在许多东非和南亚国家,宫颈恶性肿瘤无论从发病率还是死亡率来看,都被认为是影响妇女的最危险癌症之一:本研究旨在提出一种高效的自动系统,用于分割宫颈图像中的癌变区域:方法:所提出的技术包括预处理、使用优化特征集进行特征提取、分类和分割。使用高斯滤波技术对原始宫颈图像进行平滑处理,然后从增强后的宫颈图像中提取局部二进制模式(LBP)和灰度共现矩阵(GLCM)特征。LBP 特征捕捉掩膜窗口内的像素关系,而 GLCM 特征则量化图像中所有像素的能量指标。这些特征可用于区分正常和异常的宫颈图像。使用遗传算法(GA)作为优化方法对提取的特征进行优化,并使用协同自适应神经模糊推理系统(CANFIS)分类方法对优化后的特征集进行分类。随后,采用形态学分割技术对不规则宫颈图像进行分类,识别并分割其中的恶性区域:结果:提出的方法灵敏度为 99.09%,特异度为 99.39%,准确度为 99.36%:结论:与最先进的技术相比,所提出的方法表现出更优越的性能,其结果已得到放射科专家的验证。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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