[Clinical characteristics and prognostic criteria in alcoholic hepatitis and alcoholic hepatitis with cirrhosis].

J F García Rodríguez, S Tomé Martínez de Rituerto, F Martínez Vázquez, F Gude Sanpedro, I Rodríguez López, E Barrio Gómez
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Abstract

A comparative study of clinical and biological features and of the immediate prognosis was made in 46 patients with alcoholic hepatitis and 19 patients with alcoholic hepatitis with liver cirrhosis. The presence of cirrhosis has different clinical manifestations and a more intense alteration of albumin, prothrombin, total bilirubin and immunoglobulins (p less than 0.01). The development of ascites, encephalopathy and hepatorenal syndrome (p less than 0.05) and albumin, prothrombin and total bilirubin values at admission (p less than 0.01) were the best parameters to identify the patients with a poorer prognosis. There were no significant differences between both groups in mortality, frequency of encephalopathy or renal failure.

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酒精性肝炎和酒精性肝炎合并肝硬化的临床特点及预后标准
本文对46例酒精性肝炎患者和19例酒精性肝炎合并肝硬化患者的临床、生物学特征及即时预后进行了比较研究。肝硬化有不同的临床表现,白蛋白、凝血酶原、总胆红素和免疫球蛋白的改变更强烈(p < 0.01)。腹水、脑病、肝肾综合征的发生情况(p < 0.05)和入院时白蛋白、凝血酶原、总胆红素值(p < 0.01)是鉴别预后较差患者的最佳参数。两组患者的死亡率、脑病发生频率和肾功能衰竭发生率均无显著差异。
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