{"title":"Stearin as a Starting Material for the Synthesis of Biologically Active Ionic Liquids","authors":"M. M. Seitkalieva, A. V. Vavina, E. N. Strukova","doi":"10.1134/S0012500823600967","DOIUrl":null,"url":null,"abstract":"<p>The possibility of using widely available stearin to produce fatty acid-derived ionic liquids (ILs) has been shown for the first time. New amphiphilic ILs based on imidazolium, pyridinium, and quaternary ammonium cations containing long-chain alkyl substituents have been prepared. The synthesized compounds have been shown to have biological activity comparable to known antimicrobial compounds. ILs with one alkyl substituent have higher cytotoxicity and antimicrobial activity compared to disubstituted derivatives.</p>","PeriodicalId":530,"journal":{"name":"Doklady Chemistry","volume":"513 2","pages":"380 - 388"},"PeriodicalIF":0.8000,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Doklady Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S0012500823600967","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The possibility of using widely available stearin to produce fatty acid-derived ionic liquids (ILs) has been shown for the first time. New amphiphilic ILs based on imidazolium, pyridinium, and quaternary ammonium cations containing long-chain alkyl substituents have been prepared. The synthesized compounds have been shown to have biological activity comparable to known antimicrobial compounds. ILs with one alkyl substituent have higher cytotoxicity and antimicrobial activity compared to disubstituted derivatives.
期刊介绍:
Doklady Chemistry is a journal that publishes new research in chemistry and chemical engineering of great significance. Initially the journal was a forum of the Russian Academy of Science and published only best contributions from Russia in the form of short articles. Now the journal welcomes submissions from any country in the English or Russian language. Every manuscript must be recommended by Russian or foreign members of the Russian Academy of Sciences.