Mahmud Omar, Mohammad Omar, Saleh Nassar, Adi Lahat, Kassem Sharif
{"title":"Genetic Associations Between Celiac Disease and Type 2 Inflammatory Diseases: A Mendelian Randomization Analysis","authors":"Mahmud Omar, Mohammad Omar, Saleh Nassar, Adi Lahat, Kassem Sharif","doi":"10.1101/2024.01.18.24301488","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Epidemiological data suggest an association with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis, however, genetic associations remain unclear, prompting this study to explore their potential genetic interplay.","PeriodicalId":501258,"journal":{"name":"medRxiv - Gastroenterology","volume":"56 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.18.24301488","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Epidemiological data suggest an association with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis, however, genetic associations remain unclear, prompting this study to explore their potential genetic interplay.
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