Sacral extradural spinal meningioma with recurrence; a case report

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-13 DOI:10.34172/ipp.2023.40603
M. Farrokhi, Abbas Khosravifarsani, Mavlonov Jaloliddin Begijonovich
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Abstract

Extradural spinal meningiomas are very uncommon, and just a scattering of clinical reports on this condition have been published. Despite being benign, epidural meningiomas exhibit a higher recurrence rate compared to typical meningiomas. In this case report, we described a case of sacral extradural spinal meningioma with several episodes of recurrence and discussed the clinical characteristics, radiological features, and management, along with follow-up details. A 19-year-old woman with back discomfort and lower extremity numbness. Magnetic resonance imaging (MRI) revealed a tumor on the left posterolateral S1–S2 spinal cord. L5–S3 hemilaminectomy and foraminotomy were performed. After three years, the patient had bilateral L4–S1 laminectomy and radiotherapy for tumor recurrence. Two years later, the patient presented with pain and paresthesia in the lower limbs and was diagnosed with a tumor recurrence once more. Due to sacral area adhesion from earlier surgeries and radiation, the patient received CyberKnife radiation instead of tumor resection. No complaints or signs of recurrence were detected during follow-up examinations. Extradural spinal meningiomas are uncommon and can occasionally be misidentified as malignant metastatic tumors both before and during surgery. This misclassification could potentially lead to alterations in the recommended surgical approach. Although epidural spinal meningiomas are often benign, their long-term prognosis is uncertain, and the recurrence rate is higher than ordinary meningiomas. Hence, lengthy monitoring is necessary to identify any recurrence risk (like our case).
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骶骨硬膜外脊髓脑膜瘤复发;病例报告
脊髓硬膜外脑膜瘤非常罕见,关于这种疾病的临床报告也寥寥无几。硬膜外脑膜瘤虽然是良性肿瘤,但与典型脑膜瘤相比,复发率较高。在本病例报告中,我们描述了一例多次复发的骶骨硬膜外脊膜瘤,并讨论了其临床特点、放射学特征、处理方法以及随访细节。患者为一名 19 岁女性,背部不适,下肢麻木。磁共振成像(MRI)显示左侧 S1-S2 脊髓后外侧有一肿瘤。患者接受了 L5-S3 半椎板切除术和椎板切除术。三年后,患者因肿瘤复发接受了双侧 L4-S1 椎板切除术和放疗。两年后,患者出现下肢疼痛和麻痹,再次被诊断为肿瘤复发。由于之前的手术和放疗导致骶骨部位粘连,患者接受了 CyberKnife 放射治疗,而不是肿瘤切除术。随访检查中未发现复发的主诉或迹象。脊髓外膜脑膜瘤并不常见,在手术前和手术中偶尔会被误诊为恶性转移瘤。这种错误分类有可能导致推荐的手术方法发生改变。虽然脊髓硬膜外脑膜瘤通常是良性的,但其长期预后并不确定,复发率也高于普通脑膜瘤。因此,有必要进行长期监测,以发现复发风险(如我们的病例)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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