Revolutionizing C–H Activation Reactions: Harnessing Green Solvents for Sustainable Catalysis

Synthesis Pub Date : 2024-01-10 DOI:10.1055/a-2241-6858
Dewal S. Deshmukh, Nikunjkumar Vagadiya, Samadhan Jagatap, Pravin Malasane
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Abstract

This review deals with the developing field of C–H activation reactions and particularly focuses on green catalysis through the use of environmentally friendly solvents. It evaluates the effects of these solvents on reactions outcomes, environmental aspects and general efficacy pointing out their advantages lead to greater selectivity, lower level of toxicity and enhanced reaction rates. Water and biobased alternatives such as Polyethylene glycols, Ethanol, Gamma-valerolactone, Methanol, p-cymene or 2-methyltetrahydrofurane, Glycerol or Di ethyl carbonate represent representative examples of such solvents. Its scope encompasses the study of different methodologies, catalysts, and reaction conditions that help to develop C–H activation reactions with green solvents.

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革新 C-H 活化反应:利用绿色溶剂实现可持续催化
这篇综述涉及不断发展的 C-H 活化反应领域,尤其关注通过使用环境友好型溶剂实现绿色催化。它评估了这些溶剂对反应结果、环境问题和一般功效的影响,指出它们的优点是选择性更高、毒性更低和反应速度更快。水和生物基替代品(如聚乙二醇、乙醇、γ-戊内酯、甲醇、对-甲苯或 2-甲基四氢呋喃、甘油或碳酸二乙酯)是此类溶剂的代表。其研究范围包括不同的方法、催化剂和反应条件,这些都有助于利用绿色溶剂开发 C-H 活化反应。
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