{"title":"Mechanism analysis of toxic and side effects of chemicals on human body","authors":"Yinzhi Shen","doi":"10.54254/2753-8818/29/20240772","DOIUrl":null,"url":null,"abstract":"The exposure of the human body to different chemical substances poses a critical hazard to public well-being. Chemical toxicity is fundamentally ascribed to the disturbance of typical biological processes and can result in unfavorable health results. Understanding the components by which chemical substances apply their harmful impacts is vital for surveying and moderating these dangers. In this research, it will discuss the different routes of exposure, such as inhalation ingestion and dermal contact through which chemicals can enter the body. This research investigates the complex instruments at the atomic and cellular levels, counting oxidative stretch DNA harm and disturbance of enzymatic pathways by which harmful impacts are actuated. The evaluation of chemical toxicity includes a range of toxicological considerations, including acute and chronic toxicity tests, genotoxicity measures, and carcinogenicity evaluations. The development of reliable toxicity evaluation strategies, such as in vitro and in silico models, plays an urgent part in predicting the adverse impacts of chemical substances. Administrative systems and hazard evaluation techniques are discussed to guarantee peoples and the environments security. A comprehensive understanding of the components and assessment of poisonous side impacts is essential for defending open health and minimizing the hindering effects of chemical exposure.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"59 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Theoretical and Natural Science","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.54254/2753-8818/29/20240772","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The exposure of the human body to different chemical substances poses a critical hazard to public well-being. Chemical toxicity is fundamentally ascribed to the disturbance of typical biological processes and can result in unfavorable health results. Understanding the components by which chemical substances apply their harmful impacts is vital for surveying and moderating these dangers. In this research, it will discuss the different routes of exposure, such as inhalation ingestion and dermal contact through which chemicals can enter the body. This research investigates the complex instruments at the atomic and cellular levels, counting oxidative stretch DNA harm and disturbance of enzymatic pathways by which harmful impacts are actuated. The evaluation of chemical toxicity includes a range of toxicological considerations, including acute and chronic toxicity tests, genotoxicity measures, and carcinogenicity evaluations. The development of reliable toxicity evaluation strategies, such as in vitro and in silico models, plays an urgent part in predicting the adverse impacts of chemical substances. Administrative systems and hazard evaluation techniques are discussed to guarantee peoples and the environments security. A comprehensive understanding of the components and assessment of poisonous side impacts is essential for defending open health and minimizing the hindering effects of chemical exposure.
人体接触不同的化学物质会对公众健康造成严重危害。化学毒性从根本上说是由于典型的生物过程受到干扰,并可能导致不利的健康结果。了解化学物质产生有害影响的成分对于调查和减缓这些危险至关重要。本研究将讨论化学品进入人体的不同接触途径,如吸入、摄入和皮肤接触。这项研究将调查原子和细胞层面的复杂仪器,计算氧化伸展 DNA 的伤害和酶途径的干扰,通过这些途径产生有害影响。化学毒性评估包括一系列毒理学考虑因素,包括急性和慢性毒性试验、遗传毒性测量和致癌性评估。开发可靠的毒性评估策略,如体外和硅学模型,在预测化学物质的不利影响方面发挥着迫切的作用。讨论了管理制度和危害评估技术,以确保人类和环境的安全。全面了解毒副作用的成分和评估对于保护公众健康和最大限度地减少化学品暴露的有害影响至关重要。