Healthcare professionals' understanding and perception of drug-related issues linked to off-label pharmacological medications used for COVID-19.

IF 4.2 2区 医学 Q1 INFECTIOUS DISEASES Expert Review of Anti-infective Therapy Pub Date : 2024-06-01 Epub Date: 2024-01-31 DOI:10.1080/14787210.2024.2310004
Muhammad Zeeshan Munir, Amer Hayat Khan, Tahir Mehmood Khan
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Abstract

Background: To evaluate the opinions of healthcare workers regarding drug therapy problems linked to anti-infective medicines used for the treatment of COVID-19 infection in Pakistan.

Research methodology: This cross-sectional study was conducted from January to October 2022 using a self-administered questionnaire developed by the authors, having three sections: demographics, knowledge, and perception. The study was validated by research experts and pilot-tested on 30 subjects. The study included medical doctors, nurses, pharmacists from Punjab's government and private medical institutes.

Results: In this study, 382 of 400 participants replied. The mean knowledge score was 9.52 (SD 2.97), showing that participants had adequate knowledge of COVID-19 pharmacological interventions. The knowledge scores were significantly higher of those who treated COVID-19 patients and were from Lahore. Many doctors considered that elderly patients and those with blood disorders were at greater risk of experiencing drug-related problems. Most pharmacists support electronic prescription systems. Many doctors thought the lack of unified treatment guidelines, multiple prescribers, and self-medication were key obstacles in managing COVID-19 patients.

Conclusion: Most respondents had adequate knowledge. Older patients with comorbidities are at risk of adverse effects. Self-medication, polypharmacy, and multiple prescriptions can lead to misdiagnosis and complications. Electric prescriptions, team effort, and training programs can decrease these issues.

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医护人员对与 COVID-19 标签外用药相关的药物问题的理解和看法。
研究背景目的:评估巴基斯坦医护人员对用于治疗 COVID-19 感染的抗感染药物相关药物治疗问题的看法:这项横断面研究于 2022 年 1 月至 10 月进行,采用的是作者自制的调查问卷,包括三个部分:人口统计学、知识和认知。该研究经研究专家验证,并在 30 名受试者中进行了试点测试。研究对象包括旁遮普省政府和私立医疗机构的医生、护士和药剂师:在这项研究中,400 名参与者中有 382 人作答。平均知识得分为 9.52(标准差为 2.97),表明参与者对 COVID-19 药物干预措施有足够的了解。治疗 COVID-19 患者和来自拉合尔的参与者的知识得分明显更高。许多医生认为,老年患者和患有血液疾病的患者遇到药物相关问题的风险更大。大多数药剂师支持电子处方系统。许多医生认为,缺乏统一的治疗指南、多个处方者和自行用药是管理 COVID-19 患者的主要障碍:结论:大多数受访者有足够的知识。有合并症的老年患者面临不良反应的风险。自我用药、多重用药和多次开药会导致误诊和并发症。电子处方、团队合作和培训计划可以减少这些问题。
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来源期刊
CiteScore
11.20
自引率
0.00%
发文量
66
审稿时长
4-8 weeks
期刊介绍: Expert Review of Anti-Infective Therapy (ISSN 1478-7210) provides expert reviews on therapeutics and diagnostics in the treatment of infectious disease. Coverage includes antibiotics, drug resistance, drug therapy, infectious disease medicine, antibacterial, antimicrobial, antifungal and antiviral approaches, and diagnostic tests.
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