Yasser Ragab , Khalid Alhusseiny , Amr A. Saad , Yasser Emad , Farida Y. Emad , Johannes J. Rasker
{"title":"Extra-articular calcification of the lateral collateral ligament (LCL) presenting with recurrent acute knee periarthritis: A case-based review","authors":"Yasser Ragab , Khalid Alhusseiny , Amr A. Saad , Yasser Emad , Farida Y. Emad , Johannes J. Rasker","doi":"10.1016/j.ejr.2024.01.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Aim of the work</h3><p>To present a case with extra-articular calcification of the lateral collateral ligament<span> (LCL) presenting with recurrent acute knee periarthritis.</span></p></div><div><h3>Case presentation</h3><p><span>A 53-year-old Saudi male patient presented with acute onset of right-sided knee pain, localized swelling and tenderness along the lateral aspect after sport related activity. He reported a similar attack at the same knee joint a few years earlier. Plain X-ray and magnetic resonance imaging (MRI) after the initial attack showed calcification along the LCL. On examination, the patient had mild knee effusion, painful knee extension, and localized swelling along the LCL. A recent MRI and complementary computerized tomography (CT) showed a fragmented calcific shadow along the LCL. The latter was associated with soft tissue hyperintensity, which indicated extensive local inflammatory reaction. After ruling out internal derangement and infection, it was concluded that the patient had an acute episode of </span><em>peri</em>-arthritis caused by calcification along the LCL of the affected knee joint. Intramuscular (IM) betemetazone sodium dipropionate/phosphate was used to treat the <em>peri</em><span>-arthritis and as such deposits may cause a potent neutrophilic chemotactic response and intense inflammation, colchicine<span> was added for its anti-inflammatory properties and other known mechanisms that are effective in treating crystal-induced arthritis. On the second day following treatment, a significant improvement was seen. A case-based review was presented.</span></span></p></div><div><h3>Conclusion</h3><p>Despite the rare incidence of symptomatic LCL calcification, fragmentation of the calcific deposits may lead to acute intense inflammatory exacerbation and <em>peri</em>-arthritis. Successful and optimum management may involve IM steroid with oral colchicine.</p></div>","PeriodicalId":46152,"journal":{"name":"Egyptian Rheumatologist","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Egyptian Rheumatologist","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1110116424000139","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aim of the work
To present a case with extra-articular calcification of the lateral collateral ligament (LCL) presenting with recurrent acute knee periarthritis.
Case presentation
A 53-year-old Saudi male patient presented with acute onset of right-sided knee pain, localized swelling and tenderness along the lateral aspect after sport related activity. He reported a similar attack at the same knee joint a few years earlier. Plain X-ray and magnetic resonance imaging (MRI) after the initial attack showed calcification along the LCL. On examination, the patient had mild knee effusion, painful knee extension, and localized swelling along the LCL. A recent MRI and complementary computerized tomography (CT) showed a fragmented calcific shadow along the LCL. The latter was associated with soft tissue hyperintensity, which indicated extensive local inflammatory reaction. After ruling out internal derangement and infection, it was concluded that the patient had an acute episode of peri-arthritis caused by calcification along the LCL of the affected knee joint. Intramuscular (IM) betemetazone sodium dipropionate/phosphate was used to treat the peri-arthritis and as such deposits may cause a potent neutrophilic chemotactic response and intense inflammation, colchicine was added for its anti-inflammatory properties and other known mechanisms that are effective in treating crystal-induced arthritis. On the second day following treatment, a significant improvement was seen. A case-based review was presented.
Conclusion
Despite the rare incidence of symptomatic LCL calcification, fragmentation of the calcific deposits may lead to acute intense inflammatory exacerbation and peri-arthritis. Successful and optimum management may involve IM steroid with oral colchicine.
病例介绍 一位 53 岁的沙特籍男性患者在参加完体育相关活动后出现急性右侧膝关节疼痛、局部肿胀和外侧压痛。几年前,他曾报告过同一膝关节的类似症状。初次发病后的 X 光平片和磁共振成像(MRI)显示,LCL 出现钙化。经检查,患者膝关节轻度积液,膝关节伸展疼痛,LCL沿线局部肿胀。最近的核磁共振成像(MRI)和辅助计算机断层扫描(CT)显示,LCL沿线有碎裂的钙化阴影。后者伴有软组织高密度,表明局部有广泛的炎症反应。在排除了内脏病变和感染的可能性后,得出的结论是,患者患上的膝关节LCL钙化导致了急性关节周围炎。肌肉注射(IM)倍他米松二丙酸钠/磷酸酯被用于治疗关节周围炎,由于这些沉积物可能会引起强烈的中性粒细胞趋化反应和强烈的炎症,因此加入了秋水仙碱,因为秋水仙碱具有抗炎特性和其他已知机制,可有效治疗晶体诱发的关节炎。在治疗后的第二天,患者的病情有了明显改善。结论尽管无症状的 LCL钙化很少发生,但钙化沉积物的碎裂可能会导致急性剧烈炎症加重和关节炎周围炎。成功和最佳的治疗方法可能是在使用 IM 类固醇的同时口服秋水仙碱。