Characteristics of endemic human coronavirus infections during times of COVID-19 pandemic.

IF 0.6 4区医学 Q3 MEDICINE, GENERAL & INTERNAL Medicina-buenos Aires Pub Date : 2024-01-01

Eric E Crocci, Delfina Schreiner, Emilia A García, Esteban C Nannini, Manuela Cobos, Paula Doubik, Juan P Balbuena, Agustin Romandetta, Bettina Cooke, María F Alzogaray, Elsa Baumeister, Analia Mykietiuk

{"title":"Characteristics of endemic human coronavirus infections during times of COVID-19 pandemic.","authors":"Eric E Crocci, Delfina Schreiner, Emilia A García, Esteban C Nannini, Manuela Cobos, Paula Doubik, Juan P Balbuena, Agustin Romandetta, Bettina Cooke, María F Alzogaray, Elsa Baumeister, Analia Mykietiuk","doi":"","DOIUrl":null,"url":null,"abstract":"Introduction: After the implementation of mitigation strategies during the COVID-19 pandemic, the incidence of respiratory viruses, including human coronaviruses (HCoV), experienced a significant decrease. The aim of this study is to characterize the epidemiology and clinical aspects of HCoV infections in ambulatory adults during COVID-19 pandemic times.Methods: descriptive, prospective, longitudinal study performed in a private hospital in La Plata, Buenos Aires, Argentina between November 2020 and October 2022; 458 outpatient adults with upper respiratory tract infections (URTI) were studied undergoing clinical and microbiological follow-up.Results: 44 (9.6%) subjects were positive by multiplex PCR for HCoV. 14 of them for 229E (31.8%), 13 for OC43 (29.5%), 11 for HKU-1 (25.1%) and 6 for NL63 (13.6%). A repeated PCR was positive for the same HCoV in 19 (57%) of 33 patients on day 3-5. No hospitalizations or deaths were reported.Discussion: Endemic HCoV caused a significant proportion of URTI among outpatient adults during COVID-19-related restrictions times. An alternating pattern of circulation between alfa-HCoV and beta-HCoV was observed.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"102-107"},"PeriodicalIF":0.6000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina-buenos Aires","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: After the implementation of mitigation strategies during the COVID-19 pandemic, the incidence of respiratory viruses, including human coronaviruses (HCoV), experienced a significant decrease. The aim of this study is to characterize the epidemiology and clinical aspects of HCoV infections in ambulatory adults during COVID-19 pandemic times.

Methods: descriptive, prospective, longitudinal study performed in a private hospital in La Plata, Buenos Aires, Argentina between November 2020 and October 2022; 458 outpatient adults with upper respiratory tract infections (URTI) were studied undergoing clinical and microbiological follow-up.

Results: 44 (9.6%) subjects were positive by multiplex PCR for HCoV. 14 of them for 229E (31.8%), 13 for OC43 (29.5%), 11 for HKU-1 (25.1%) and 6 for NL63 (13.6%). A repeated PCR was positive for the same HCoV in 19 (57%) of 33 patients on day 3-5. No hospitalizations or deaths were reported.

Discussion: Endemic HCoV caused a significant proportion of URTI among outpatient adults during COVID-19-related restrictions times. An alternating pattern of circulation between alfa-HCoV and beta-HCoV was observed.

微信好友朋友圈 QQ好友复制链接

本刊更多论文

COVID-19 大流行期间地方性人类冠状病毒感染的特征。

导言：在 COVID-19 大流行期间实施缓解策略后，包括人类冠状病毒 (HCoV) 在内的呼吸道病毒发病率显著下降。方法：2020 年 11 月至 2022 年 10 月期间，在阿根廷布宜诺斯艾利斯拉普拉塔市的一家私立医院开展了描述性、前瞻性纵向研究，对 458 名患有上呼吸道感染（URTI）的门诊成人进行了临床和微生物学随访：结果：44 名受试者（9.6%）的多重 PCR 检测结果呈 HCoV 阳性。其中 229E 阳性 14 例（31.8%），OC43 阳性 13 例（29.5%），HKU-1 阳性 11 例（25.1%），NL63 阳性 6 例（13.6%）。在 33 名患者中，有 19 人（57%）在第 3-5 天重复 PCR 检测时发现同一种 HCoV 呈阳性。无住院或死亡报告：讨论：在与 COVID-19 相关的限制期内，地方性 HCoV 在门诊成人尿路感染中占很大比例。观察到α-HCoV和β-HCoV交替循环的模式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊