Safety Assessment of Zinc Salts as Used in Cosmetics.

IF 1.2 4区 医学 Q4 PHARMACOLOGY & PHARMACY International Journal of Toxicology Pub Date : 2024-04-01 Epub Date: 2024-01-27 DOI:10.1177/10915818241227124
Laura N Scott, Monice Fiume, Jinqiu Zhu, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Bart Heldreth
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Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 27 inorganic and organometallic zinc salts as used in cosmetic formulations; these salts are specifically of the 2+ (II) oxidation state cation of zinc. These ingredients included in this report have various reported functions in cosmetics, including hair conditioning agents, skin conditioning agents, cosmetic astringents, cosmetic biocides, preservatives, oral care agents, buffering agents, bulking agents, chelating agents, and viscosity increasing agents. The Panel reviewed the relevant data for these ingredients, and concluded that these 27 ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating.

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化妆品中使用的锌盐的安全性评估。
化妆品成分安全专家小组(专家小组)对化妆品配方中使用的 27 种无机和有机金属锌盐的安全性进行了评估;这些锌盐特别是锌的 2+ (II) 氧化态阳离子。据报告,本报告中的这些成分在化妆品中具有各种功能,包括头发调理剂、皮肤调理剂、化妆品收敛剂、化妆品杀菌剂、防腐剂、口腔护理剂、缓冲剂、膨松剂、螯合剂和增粘剂。专家小组审查了这些成分的相关数据,得出结论认为,按照本安全评估中所述的现行使用方法和浓度,这 27 种成分在配制成无刺激性的化妆品中是安全的。
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来源期刊
CiteScore
3.40
自引率
4.50%
发文量
53
审稿时长
4.5 months
期刊介绍: The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.
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