A 42-Year-Old Woman With Rapidly Expanding White Matter Lesions: From the National Multiple Sclerosis Society Case Conference Proceedings.

IF 7.8 1区 医学 Q1 CLINICAL NEUROLOGY Neurology® Neuroimmunology & Neuroinflammation Pub Date : 2024-05-01 Epub Date: 2024-01-29 DOI:10.1212/NXI.0000000000200201
Tolulope O Amiola, Unsong Oh, Hope Richard, Scott D Newsome, Jennifer Graves, Scott S Zamvil, Myla D Goldman
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Abstract

A 42-year-old woman and active cocaine user complained of subacutely worsening blurred vision and imbalance. Examination of the brain MRI showed rapidly expanding white matter lesions. Brain biopsy was consistent with inflammatory demyelination. Given an unusual presentation and a history of cocaine use, a broad differential diagnosis was considered including neurologic toxidromes.

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一名 42 岁女性的白质病变迅速扩大:全国多发性硬化症协会病例会议论文集》。
一名 42 岁的女性,可卡因的积极使用者,主诉视力模糊和失衡亚急性恶化。脑部核磁共振成像检查显示白质病变迅速扩大。脑活检结果与炎性脱髓鞘一致。考虑到患者的异常表现和可卡因使用史,医生考虑了广泛的鉴别诊断,包括神经系统毒血症。
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来源期刊
CiteScore
15.60
自引率
2.30%
发文量
219
审稿时长
8 weeks
期刊介绍: Neurology Neuroimmunology & Neuroinflammation is an official journal of the American Academy of Neurology. Neurology: Neuroimmunology & Neuroinflammation will be the premier peer-reviewed journal in neuroimmunology and neuroinflammation. This journal publishes rigorously peer-reviewed open-access reports of original research and in-depth reviews of topics in neuroimmunology & neuroinflammation, affecting the full range of neurologic diseases including (but not limited to) Alzheimer's disease, Parkinson's disease, ALS, tauopathy, and stroke; multiple sclerosis and NMO; inflammatory peripheral nerve and muscle disease, Guillain-Barré and myasthenia gravis; nervous system infection; paraneoplastic syndromes, noninfectious encephalitides and other antibody-mediated disorders; and psychiatric and neurodevelopmental disorders. Clinical trials, instructive case reports, and small case series will also be featured.
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