Micrococcus Peritonitis Complicating Peritoneal Dialysis.

Rhode Island medical journal (2013) Pub Date : 2024-02-01
Martin L Li, Ankur D Shah
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Abstract

Peritonitis, a serious complication of peritoneal dialysis (PD), can be caused by opportunistic pathogens like Micrococcus species on rare occasions. We present a case of Micrococcus sp peritonitis in a 55-year-old female with end-stage kidney disease on continuous cycling peritoneal dialysis for one year who presented with cloudy effluent. Initial treatment against Micrococcus sp with vancomycin, gentamicin, and prophylactic oral nystatin was successful. However, one month later, the patient presented with abdominal pain and dialysate culture again grew Micrococcus sp. Treatment with vancomycin was unsuccessful in resolving culture positivity. The patient was transitioned to hemodialysis for non-medical reasons and then was later restarted on PD without further peritonitis episodes. Micrococcus sp peritonitis in PD poses treatment challenges due to limited guidelines. Intraperitoneal vancomycin is commonly used to target Micrococcus isolates although there is a high incidence of treatment failure. This case report highlights the need for continued reporting to enhance identification, prevention, and patient outcomes in Micrococcus sp peritonitis during PD.

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并发腹膜透析的微球菌腹膜炎
腹膜炎是腹膜透析(PD)的一种严重并发症,在极少数情况下可由机会性病原体(如微球菌)引起。我们报告了一例微球菌腹膜炎病例,患者是一名 55 岁的女性,患有终末期肾病,已接受连续循环腹膜透析一年,并出现流出液浑浊的症状。最初使用万古霉素、庆大霉素和预防性口服硝司他丁治疗微球菌获得成功。但一个月后,患者出现腹痛,透析液培养再次发现微球菌。由于非医疗原因,患者转为血液透析,后来又重新开始进行腹膜透析,但未再发生腹膜炎。由于指南有限,腹膜透析中的微球菌腹膜炎给治疗带来了挑战。腹腔注射万古霉素通常用于治疗微球菌分离株,但治疗失败的发生率很高。本病例报告强调了继续报告的必要性,以加强腹膜透析期间微球菌腹膜炎的识别、预防和患者预后。
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