Jingwen Ji, Zafar Iqbal, Liuyan Li, Jian Sun, Pengjuan Zhou, Lijuan Zhai, Lili He, Dong Tang, Jinbo Ji, Haikang Yang, Zhixiang Yang
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引用次数: 0
Abstract
: N1-caffeoyl-N10-dihydrocaffeoylspermidine (Scotanamine D), a spermidine alkaloid isolated from various plants, is a medicinally valuable natural product. Recent studies have pointed out several health benefits of this compound. However, its synthetic procedures are still not described in the literature. We report the synthesis of this compound following two different schemes comprising multiple steps with excellent overall yields, which are 57% and 81%, respectively. These two synthetic schemes, which use commercially available and cheaper starting materials, can facilitate the large-scale manufacturing of Scotanamine D.
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Letters in Organic Chemistry publishes original letters (short articles), research articles, mini-reviews and thematic issues based on mini-reviews and short articles, in all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is to publish quality papers rapidly by taking full advantage of latest technology for both submission and review of the manuscripts.
The journal is an essential reading for all organic chemists belonging to both academia and industry.
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