Glucose-Water Synergy: An Organocatalytic System Driven synthesis of Benzimidazolo[2,3-b]quinazolinone and Benzothiazolo[2,3-b]quinazolinone Derivatives
J. Baranwal, Swastika Singh, Smriti Kushwaha, Archana Jyoti
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引用次数: 0
Abstract
A simple and efficient one-pot synthesis of quinazolinone derivatives has
been developed via a multicomponent reaction (MCR) involving the condensation of dimedone,
benzaldehyde, and 2-aminobenzimidazole/2-aminobenzothiazole.
In this work, glucose water is used as a green, reusable, environmentally benign organocatalytic solvent system to synthesize desired products.
The main benefits of this one-pot method include its excellent yields, less time, cost-effectiveness, atom economy, environment benign, and easy workup.
In conclusion, we successfully developed a green protocol for the environmentally
benign synthesis of benzimidazo/benzothiazolo quinazolinones using glucose water as an organocatalytic medium
期刊介绍：
Current Organocatalysis is an international peer-reviewed journal that publishes significant research in all areas of organocatalysis. The journal covers organo homogeneous/heterogeneous catalysis, innovative mechanistic studies and kinetics of organocatalytic processes focusing on practical, theoretical and computational aspects. It also includes potential applications of organocatalysts in the fields of drug discovery, synthesis of novel molecules, synthetic method development, green chemistry and chemoenzymatic reactions. This journal also accepts papers on methods, reagents, and mechanism of a synthetic process and technology pertaining to chemistry. Moreover, this journal features full-length/mini review articles within organocatalysis and synthetic chemistry. It is the premier source of organocatalysis and synthetic methods related information for chemists, biologists and engineers pursuing research in industry and academia.
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