Carla Rosero, L. Baldeón, Valeria Alulema, Adriana Rueda, Lorena Vaca, Daniela Galarza, Cesar Prócel
{"title":"Cutaneous tuberculosis, different clinical spectrum of the same disease: the importance of pre-test probability","authors":"Carla Rosero, L. Baldeón, Valeria Alulema, Adriana Rueda, Lorena Vaca, Daniela Galarza, Cesar Prócel","doi":"10.4081/dr.2024.9770","DOIUrl":null,"url":null,"abstract":"Antecedents. This report presents three cases of Cutaneous tuberculosis CTB that were diagnosed at Calderon Hospital, Quito, Ecuador. The first case was Tuberculosis verrucosa cutis (TVC) in a 44-year-old man with circinated erythematous areas with ulcerated nodules and verruciform plaques from the right lower limb to the hip. The second case was Lupus Vulgaris (LV) in a 50- year-old female with one-year history of pruritic dermatosis in the left ciliary area. The third case was Scrofuloderma in a 23-year-old man with erythematous nodules that drain caseous material at neck, thorax and axillary region. Almost all laboratory tests that were available turned out to have limitations as a diagnostic tool. Conclusion. In immunocompromised and high-risk individuals with atypical lesions, it is important to correlate clinical and epidemiological characteristics with the pretest probability in order to optimize indicators and determine or exclude out the diagnosis.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":"89 9","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/dr.2024.9770","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
Antecedents. This report presents three cases of Cutaneous tuberculosis CTB that were diagnosed at Calderon Hospital, Quito, Ecuador. The first case was Tuberculosis verrucosa cutis (TVC) in a 44-year-old man with circinated erythematous areas with ulcerated nodules and verruciform plaques from the right lower limb to the hip. The second case was Lupus Vulgaris (LV) in a 50- year-old female with one-year history of pruritic dermatosis in the left ciliary area. The third case was Scrofuloderma in a 23-year-old man with erythematous nodules that drain caseous material at neck, thorax and axillary region. Almost all laboratory tests that were available turned out to have limitations as a diagnostic tool. Conclusion. In immunocompromised and high-risk individuals with atypical lesions, it is important to correlate clinical and epidemiological characteristics with the pretest probability in order to optimize indicators and determine or exclude out the diagnosis.
期刊介绍:
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.