Total hip arthroplasty performed in summer is not associated with increased risk of revision due to prosthetic joint infection: a cohort study on 58 449 patients with osteoarthritis from the Danish Hip Arthroplasty Register

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-23 DOI:10.5194/jbji-9-1-2024
Rajzan Joanroy, Jens Kjølseth Møller, Sophie Gubbels, Søren Overgaard, C. Varnum
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Abstract

Abstract. Aims: Danish surveillance data indicated a higher risk of revision due to prosthetic joint infection (PJI) following total hip arthroplasty (THA) performed during the summer season. We investigated the association between summer and revision risk following primary THA. Methods: This study identified 58 449 patients from the Danish Hip Arthroplasty Register (DHR) with unilateral primary THA due to osteoarthritis from 2010–2018. From Danish Health Registries, we retrieved information on Charlson Comorbidity Index (CCI), immigration, and death and microbiological data on intraoperative biopsies and cohabitation status. Meteorological data were received from the Danish Meteorological Institute. Summer was defined as June–September, and THAs performed during October–May were used as controls. The primary outcome was revision due to PJI: the composite of revision with ≥2 culture-positive biopsies or reported PJI to the DHR. The secondary outcome was any revision. The cumulative incidences of revision and the corresponding adjusted relative risk (RR) with 95 % confidence intervals (CI) were calculated by season of the primary THA. Results: A total of 1507 patients were revised, and 536 were due to PJI. The cumulative incidence for THAs performed during summer and the rest of the year was 1.1 % (CI 1.0–1.3) and 1.1 % (CI 1.0–1.2) for PJI revision and 2.7 % (CI 2.5–3.0) and 2.5 % (CI 2.4–2.7) for any revision, respectively. The adjusted RR for THAs performed during summer vs. the rest of the year for PJI revision and any revision was 1.1 (CI 0.9–1.3) and 1.1 (CI 1.0–1.2), respectively. Conclusion: We found no association between summer and the risk of PJI revision or any revision in a northern European climate.
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夏季进行的全髋关节置换术与假体关节感染导致的翻修风险增加无关:对丹麦髋关节置换术登记册中的 58 449 名骨关节炎患者进行的队列研究
摘要:丹麦目的:丹麦的监测数据显示,在夏季进行全髋关节置换术(THA)后,因假体关节感染(PJI)而导致翻修的风险较高。我们研究了夏季与初次全髋关节置换术后翻修风险之间的关系。方法:本研究从丹麦髋关节置换术登记(DHR)中确定了 2010-2018 年间因骨关节炎接受单侧原发性 THA 的 58 449 例患者。我们从丹麦健康登记处获取了夏尔森综合症指数(CCI)、移民和死亡信息,以及术中活检和同居状态的微生物学数据。气象数据来自丹麦气象研究所。夏季定义为 6 月至 9 月,10 月至 5 月进行的 THAs 作为对照。主要结果是因PJI导致的翻修:翻修与≥2次培养阳性活检或向DHR报告PJI的复合结果。次要结果是任何翻修。按初次 THA 的季节计算翻修的累积发生率和相应的调整后相对风险 (RR) 及 95 % 置信区间 (CI)。结果:共有 1507 例患者进行了翻修,其中 536 例是由于 PJI 引起的。在夏季和其他季节进行的 THA 的累计发病率分别为:PJI 修复为 1.1 %(CI 1.0-1.3)和 1.1 %(CI 1.0-1.2),任何修复为 2.7 %(CI 2.5-3.0)和 2.5 %(CI 2.4-2.7)。夏季进行的 THAs 与一年中其他时间进行的 THAs 相比,PJI 修复和任何修复的调整 RR 分别为 1.1 (CI 0.9-1.3) 和 1.1 (CI 1.0-1.2)。结论我们发现,在北欧气候条件下,夏季与PJI翻修或任何翻修的风险之间没有关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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