Chinese Multidisciplinary Expert Consensus on Immune Checkpoint Inhibitor (ICI)-Based Combination Therapy for Hepatocellular Carcinoma (2023 Edition)

IF 3.8 2区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY ACS Chemical Biology Pub Date : 2024-01-16 DOI:10.1159/000535496
Xiufeng Liu, Yinying Lu, Weiping Zhou, Tao Peng, Jie Zhou, Huaqiang Bi, Feng Xia, Xiaoping Chen
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Abstract

Immune checkpoint inhibitor (ICI)-based combination therapy modalities for hepatocellular carcinoma (HCC) have achieved significant efficacy in clinical research and practice and have become the mainstay for the treatment of unresectable HCC. To better help clinicians use combination immunotherapy drugs and regimens rationally, effectively, and safely, the editorial board facilitated a discussion with multidisciplinary experts in the field, adopted the "Delphi" consensus formation method, and finally revised and completed the "Chinese Multidisciplinary Expert Consensus on the Immune Checkpoint Inhibitors (ICIs)-Based Combination Therapy for Hepatocellular Carcinoma (2023 Edition)" on the basis of the 2021 edition. This consensus primarily focuses on the principles and methods of clinical practice of combination therapy based on ICIs, aiming to summarize the recommendations for clinical application based on the latest research and expert experience and provide application guidance for clinicians.
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基于免疫检查点抑制剂(ICI)的肝细胞癌联合疗法中国多学科专家共识(2023 年版)
以免疫检查点抑制剂(ICI)为基础的肝细胞癌(HCC)联合治疗模式在临床研究和实践中取得了显著疗效,已成为治疗无法切除的肝细胞癌的主要手段。为了更好地帮助临床医生合理、有效、安全地使用联合免疫治疗药物和方案,编委会召集该领域多学科专家进行讨论,采用 "德尔菲 "共识形成法,最终在2021年版的基础上修订完成了《基于免疫检查点抑制剂(ICIs)的肝细胞癌联合治疗中国多学科专家共识(2023年版)》。该共识主要针对基于ICIs的联合治疗临床实践的原则和方法,旨在根据最新研究和专家经验总结临床应用建议,为临床医生提供应用指导。
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来源期刊
ACS Chemical Biology
ACS Chemical Biology 生物-生化与分子生物学
CiteScore
7.50
自引率
5.00%
发文量
353
审稿时长
3.3 months
期刊介绍: ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. The journal also serves as a forum to facilitate the communication between biologists and chemists that will translate into new research opportunities and discoveries. Results will be published in which molecular reasoning has been used to probe questions through in vitro investigations, cell biological methods, or organismic studies. We welcome mechanistic studies on proteins, nucleic acids, sugars, lipids, and nonbiological polymers. The journal serves a large scientific community, exploring cellular function from both chemical and biological perspectives. It is understood that submitted work is based upon original results and has not been published previously.
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