Role of Calcineurin Inhibitors in the Management of Atopic Dermatitis in Children

K. Efendieva, L. S. Namazova-Baranova, Juliya G. Levina, V. Kalugina, A. Alekseeva, Elena V. Vishneva, K. Volkov
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Abstract

Atopic dermatitis (AD) is a widespread chronic inflammatory skin disease that has a significant impact on various aspects of patient's life. This review presents modern view on AD pathophysiology, its correlation with other concomitant diseases, and covers practical aspects of external anti-inflammatory therapy implementation. The analysis of clinical studies has shown the significant role of calcineurin inhibitors in the effective treatment of AD in children from its first manifestations at early age.
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降钙素蛋白抑制剂在治疗儿童特应性皮炎中的作用
特应性皮炎(AD)是一种广泛存在的慢性炎症性皮肤病,对患者生活的各个方面都有重大影响。这篇综述介绍了特应性皮炎病理生理学的现代观点及其与其他并发疾病的相关性,并涵盖了外部抗炎疗法的实际应用方面。临床研究分析表明,钙神经蛋白酶抑制剂在有效治疗儿童AD方面发挥着重要作用,因为AD在儿童幼年时期就已开始显现。
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