Network Reorganization for Neurophysiological and Behavioral Recovery Following Stroke.

Yuan Qi, Yujie Xu, Huailu Wang, Qiujia Wang, Meijie Li, Bo Han, Haijie Liu
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Abstract

Stroke continues to be the main cause of motor disability worldwide. While rehabilitation has been promised to improve recovery after stroke, efficacy in clinical trials has been mixed. We need to understand the cortical recombination framework to understand how biomarkers for neurophysiological reorganized neurotechnologies alter network activity. Here, we summarize the principles of the movement network, including the current evidence of changes in the connections and function of encephalic regions, recovery from stroke and the therapeutic effects of rehabilitation. Overall, improvements or therapeutic effects in limb motor control following stroke are correlated with the effects of interhemispheric competition or compensatory models of the motor supplementary cortex. This review suggests that future research should focus on cross-regional communication and provide fundamental insights into further treatment and rehabilitation for post-stroke patients.

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中风后神经生理和行为恢复的网络重组
中风仍然是全球运动障碍的主要原因。虽然人们承诺它能改善中风后的恢复,但临床试验的疗效却参差不齐。我们需要了解皮层重组框架,以了解神经生理重组神经技术的生物标志物如何改变网络活动。在此,我们总结了运动网络的原理,包括目前有关脑区连接和功能变化、中风后恢复和康复治疗效果的证据。总体而言,中风后肢体运动控制的改善或治疗效果与大脑半球间竞争或运动辅助皮层代偿模型的效果相关。这篇综述建议未来的研究应关注跨区域交流,并为中风后患者的进一步治疗和康复提供基础性见解。
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