Management of medication overuse headache.

Domenico D'Amico, Licia Grazzi, Stewart J Tepper
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Abstract

Medication overuse headache (MOH) is a secondary headache characterized by frequent use of acute or symptomatic migraine medications at a sufficient frequency to transform patients from episodic to chronic migraine. MOH represents a significant medical problem, with a serious burden on patients' lives and on society as a whole. MOH patients often have additional comorbidities, and the clinical challenge of helping patients reduce acute medication use and revert to episodic headache can be marked. Treatment includes education and prevention; withdrawal programs; pharmacological prophylaxis; multidisciplinary therapies with behavioral and noninvasive neuromodulation options; and scheduled, frequent follow-up to prevent relapses. The advent of anti-CGRP therapy monoclonal antibodies may provide an alternative to more extensive programs for less complex patients. This review also provides guidance for which patients may benefit most from coordinated integrated programs.

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用药过度头痛的管理。
药物过度使用性头痛(MOH)是一种继发性头痛,其特点是频繁使用急性或症状性偏头痛药物,使用频率足以使患者从发作性偏头痛转变为慢性偏头痛。偏头痛是一个重大的医学问题,给患者的生活和整个社会造成严重负担。偏头痛患者通常还伴有其他并发症,帮助患者减少急性用药并恢复发作性头痛可能是一项巨大的临床挑战。治疗包括教育和预防;戒断计划;药物预防;多学科疗法,包括行为和非侵入性神经调节选择;以及定期、频繁的随访,以防止复发。抗 CGRP 治疗单克隆抗体的出现可能会为病情不太复杂的患者提供一个替代更广泛治疗方案的选择。本综述还为哪些患者可能从协调的综合方案中获益最多提供了指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Handbook of clinical neurology
Handbook of clinical neurology Medicine-Neurology (clinical)
CiteScore
4.10
自引率
0.00%
发文量
302
期刊介绍: The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.
期刊最新文献
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